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Datasets from an interlaboratory comparison to characterize a multi-modal polydisperse sub-micrometer bead dispersion

Metadata Updated: September 30, 2025

These four data files contain datasets from an interlaboratory comparison that characterized a polydisperse five-population bead dispersion in water. A more detailed version of this description is available in the ReadMe file (PdP-ILC_datasets_ReadMe_v1.txt), which also includes definitions of abbreviations used in the data files. Paired samples were evaluated, so the datasets are organized as pairs associated with a randomly assigned laboratory number. The datasets are organized in the files by instrument type: PTA (particle tracking analysis), RMM (resonant mass measurement), ESZ (electrical sensing zone), and OTH (other techniques not covered in the three largest groups, including holographic particle characterization, laser diffraction, flow imaging, and flow cytometry). In the OTH group, the specific instrument type for each dataset is noted. Each instrument type (PTA, RMM, ESZ, OTH) has a dedicated file. Included in the data files for each dataset are: (1) the cumulative particle number concentration (PNC, (1/mL)); (2) the concentration distribution density (CDD, (1/mL·nm)) based upon five bins centered at each particle population peak diameter; (3) the CDD in higher resolution, varied-width bins. The lower-diameter bin edge (µm) is given for (2) and (3). Additionally, the PTA, RMM, and ESZ files each contain unweighted mean cumulative particle number concentrations and concentration distribution densities calculated from all datasets reporting values. The associated standard deviations and standard errors of the mean are also given. In the OTH file, the means and standard deviations were calculated using only data from one of the sub-groups (holographic particle characterization) that had n = 3 paired datasets. Where necessary, datasets not using the common bin resolutions are noted (PTA, OTH groups). The data contained here are presented and discussed in a manuscript to be submitted to the Journal of Pharmaceutical Sciences and presented as part of that scientific record.

Access & Use Information

Public: This dataset is intended for public access and use. License: See this page for license information.

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Dates

Metadata Created Date September 30, 2025
Metadata Updated Date September 30, 2025
Data Update Frequency irregular

Metadata Source

Harvested from Commerce Non Spatial Data.json Harvest Source

Additional Metadata

Resource Type Dataset
Metadata Created Date September 30, 2025
Metadata Updated Date September 30, 2025
Publisher National Institute of Standards and Technology
Maintainer
Identifier ark:/88434/mds2-2352
Data First Published 2021-03-26
Language en
Data Last Modified 2021-07-12 00:00:00
Category Bioscience:Bioprocessing, Health:Pharmaceuticals, Manufacturing:Biomanufacturing
Public Access Level public
Data Update Frequency irregular
Bureau Code 006:55
Metadata Context https://project-open-data.cio.gov/v1.1/schema/catalog.jsonld
Schema Version https://project-open-data.cio.gov/v1.1/schema
Catalog Describedby https://project-open-data.cio.gov/v1.1/schema/catalog.json
Harvest Object Id 6680c095-8c07-4c27-ba52-2405d37f228e
Harvest Source Id bce99b55-29c1-47be-b214-b8e71e9180b1
Harvest Source Title Commerce Non Spatial Data.json Harvest Source
Homepage URL https://data.nist.gov/od/id/mds2-2352
License https://www.nist.gov/open/license
Program Code 006:045
Source Datajson Identifier True
Source Hash 2c0b0065666a31c9a5adeb13a66edc0509014b54f474c82b9b8aeaef5dd69bac
Source Schema Version 1.1

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