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    • Datasets from an interlaboratory comparison to characterize a multi-modal polydisperse sub-micrometer bead dispersion

    Metadata Updated: July 29, 2022

    These four data files contain datasets from an interlaboratory comparison that characterized a polydisperse five-population bead dispersion in water. A more detailed version of this description is available in the ReadMe file (PdP-ILC_datasets_ReadMe_v1.txt), which also includes definitions of abbreviations used in the data files. Paired samples were evaluated, so the datasets are organized as pairs associated with a randomly assigned laboratory number. The datasets are organized in the files by instrument type: PTA (particle tracking analysis), RMM (resonant mass measurement), ESZ (electrical sensing zone), and OTH (other techniques not covered in the three largest groups, including holographic particle characterization, laser diffraction, flow imaging, and flow cytometry). In the OTH group, the specific instrument type for each dataset is noted. Each instrument type (PTA, RMM, ESZ, OTH) has a dedicated file. Included in the data files for each dataset are: (1) the cumulative particle number concentration (PNC, (1/mL)); (2) the concentration distribution density (CDD, (1/mL·nm)) based upon five bins centered at each particle population peak diameter; (3) the CDD in higher resolution, varied-width bins. The lower-diameter bin edge (µm) is given for (2) and (3). Additionally, the PTA, RMM, and ESZ files each contain unweighted mean cumulative particle number concentrations and concentration distribution densities calculated from all datasets reporting values. The associated standard deviations and standard errors of the mean are also given. In the OTH file, the means and standard deviations were calculated using only data from one of the sub-groups (holographic particle characterization) that had n = 3 paired datasets. Where necessary, datasets not using the common bin resolutions are noted (PTA, OTH groups). The data contained here are presented and discussed in a manuscript to be submitted to the Journal of Pharmaceutical Sciences and presented as part of that scientific record.

    Access & Use Information

    Public: This dataset is intended for public access and use. License: See this page for license information.

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    Dates

    Metadata Created Date August 10, 2021
    Metadata Updated Date July 29, 2022
    Data Update Frequency irregular

    Metadata Source

    Harvested from NIST

    Other Data Resources

    Additional Metadata

    Resource Type Dataset
    Metadata Created Date August 10, 2021
    Metadata Updated Date July 29, 2022
    Publisher National Institute of Standards and Technology
    Maintainer
    Identifier ark:/88434/mds2-2352
    Data First Published 2021-03-26
    Language en
    Data Last Modified 2021-07-12 00:00:00
    Category Bioscience:Bioprocessing, Health:Pharmaceuticals, Manufacturing:Biomanufacturing
    Public Access Level public
    Data Update Frequency irregular
    Bureau Code 006:55
    Metadata Context https://project-open-data.cio.gov/v1.1/schema/data.json
    Schema Version https://project-open-data.cio.gov/v1.1/schema
    Catalog Describedby https://project-open-data.cio.gov/v1.1/schema/catalog.json
    Harvest Object Id 50d965b3-2f2c-4bda-bf40-870ca19ea29d
    Harvest Source Id 74e175d9-66b3-4323-ac98-e2a90eeb93c0
    Harvest Source Title NIST
    Homepage URL https://data.nist.gov/od/id/mds2-2352
    License https://www.nist.gov/open/license
    Program Code 006:045
    Source Datajson Identifier True
    Source Hash f9cff1433826eef2fb3244fb9c6e71de1dcca0eb
    Source Schema Version 1.1

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