Datasets for Figures and Tables in SIX1 regulates aberrant endometrial epithelial cell differentiation and cancer trajectory

Metadata Updated: April 6, 2021

Data associated with the figures presented in this study are images, graphics, or tabulated data based on histopathologic analysis performed by a certified study pathologist or image analysis. Data for Tables 1 and 2 provide incidence, labeling scores, and p-values for statistical tests for uterine pathology and IHC expression by treatment group and timepoint or human endometrial tissue, as described in the Main Text file of the manuscript. Manual histopathologic data can be found in excel spreadsheets and are based on presence/absences (yes/no) of a pathologic finding and/or severity score as described in the manuscript (Fig. 1, 2, 3, 4). The image analysis data is based on the quantified area that is designated as “positive” for a particular immunohistochemical stain (Fig. 2, 4, and Suppl. Fig. S2). Supplementary Table 1 provides summary information on antibodies used for immunohistochemistry. Supplementary fig. S1 includes real time RT-PCR data standardized to a housekeeping gene and western blot data.

This dataset is associated with the following publication: Suen, A., W. Jefferson, C. Wood, and C. Williams. SIX1 regulates aberrant endometrial epithelial cell differentiation and cancer trajectory. Molecular Cancer Research. American Association for Cancer Research, Inc., Philadelphia, PA, USA, 17(12): 2369-2382, (2019).

Access & Use Information

Public: This dataset is intended for public access and use. License: See this page for license information.

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Fig. 1 2 3_Histopath Analysis_Charles...EXCEL
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Fig. 1_Suen-Wallach_455-C36_ Electron Micro Report.docxDOC
Fig.%201_Suen-Wallach_455-C36_%20Electron%20Micro%20Report.docx

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Fig. 2 and Supp Fig. 2_Six1 Knockout DES_Image...EXCEL
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Fig. 1 2 3_Histopath Analysis_Charles...EXCEL
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Fig. 4_Human TMA Charles Wood Analysis_052518.xlsxEXCEL
Fig.%204_Human%20TMA%20Charles%20Wood%20Analysis_052518.xlsx

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Supp Fig. 1_Real time RTPCR data all ages.xlsxEXCEL
Supp%20Fig.%201_Real%20time%20RTPCR%20data%20all%20ages.xlsx

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Fig. 2 and Supp Fig. 2_Six1 Knockout CON_Image...EXCEL
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Fig. 4_Human TMA Image Analysis_051818.xlsxEXCEL
Fig.%204_Human%20TMA%20Image%20Analysis_051818.xlsx

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References

https://doi.org/10.1158/1541-7786.mcr-19-0475

Dates

Metadata Created Date	April 6, 2021
Metadata Updated Date	April 6, 2021

Metadata Source

Data.json Data.json Metadata
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Harvested from EPA ScienceHub

Additional Metadata

Resource Type	Dataset
Metadata Created Date	April 6, 2021
Metadata Updated Date	April 6, 2021
Publisher	U.S. EPA Office of Research and Development (ORD)
Maintainer	Brian Chorley
Identifier	https://doi.org/10.23719/1503409
Data Last Modified	2019-02-13
Public Access Level	public
Bureau Code	020:00
Schema Version	https://project-open-data.cio.gov/v1.1/schema
Harvest Object Id	68bf04ad-e8f1-4569-b3e2-e7f230930dbb
Harvest Source Id	04b59eaf-ae53-4066-93db-80f2ed0df446
Harvest Source Title	EPA ScienceHub
License	https://pasteur.epa.gov/license/sciencehub-license.html
Program Code	020:095
Publisher Hierarchy	U.S. Government > U.S. Environmental Protection Agency > U.S. EPA Office of Research and Development (ORD)
Related Documents	https://doi.org/10.1158/1541-7786.mcr-19-0475
Source Datajson Identifier	True
Source Hash	a7d673d8a962f793fb4f0dc586319671d2400130
Source Schema Version	1.1

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