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Dataset for "Persistent gene expression and DNA methylation alterations linked to carcinogenic effects of dichloroacetic acid'

Published by U.S. EPA Office of Research and Development (ORD) | U.S. Environmental Protection Agency | Catalog Last Checked: August 03, 2026 at 12:50 AM | Dataset Last Updated: September 08, 2023
These spreadsheets contain the underlying data, calculations, and R code for the figures of the manuscript "Persistent gene expression and DNA methylation alterations linked to carcinogenic effects of dichloroacetic acid". The first tab of every spreadsheet contains descriptions of the data (metadata). For clarifying questions regarding the data, please contact Dr. Brian Chorley (EPA-ORD) at chorley.brian@epa.gov. If you require a review token for the sequencing datasets located in the GEO links (RNAseq and RRBS), please contact Dr. Chorley. This dataset is associated with the following publication: Carswell, G., J. Chamberlin, B. Bennett, P. Bushel, and B. Chorley. Persistent gene expression and DNA methylation alterations linked to carcinogenic effects of dichloroacetic acid. Frontiers in Oncology. Frontiers, Lausanne, SWITZERLAND, 14: 1389634, (2024).

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Complete Metadata
accessLevel public
bureauCode 
[
  "020:00"
]
contactPoint 
{
  "fn": "Brian Chorley",
  "hasEmail": "mailto:chorley.brian@epa.gov"
}
description These spreadsheets contain the underlying data, calculations, and R code for the figures of the manuscript "Persistent gene expression and DNA methylation alterations linked to carcinogenic effects of dichloroacetic acid". The first tab of every spreadsheet contains descriptions of the data (metadata). For clarifying questions regarding the data, please contact Dr. Brian Chorley (EPA-ORD) at chorley.brian@epa.gov. If you require a review token for the sequencing datasets located in the GEO links (RNAseq and RRBS), please contact Dr. Chorley. This dataset is associated with the following publication: Carswell, G., J. Chamberlin, B. Bennett, P. Bushel, and B. Chorley. Persistent gene expression and DNA methylation alterations linked to carcinogenic effects of dichloroacetic acid. Frontiers in Oncology. Frontiers, Lausanne, SWITZERLAND, 14: 1389634, (2024).
distribution 
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  {
    "title": "https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE242661",
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    "accessURL": "https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE242664"
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    "accessURL": "https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE242665"
  },
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    "title": "Figure 3A_data.xlsx",
    "mediaType": "application/vnd.openxmlformats-officedocument.spreadsheetml.sheet",
    "downloadURL": "https://pasteur.epa.gov/uploads/10.23719/1529544/Figure%203A_data.xlsx"
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identifier https://doi.org/10.23719/1529544
keyword 
[
  "DNA methylation",
  "archival samples",
  "dichloroacetic acid",
  "liver cancer",
  "transcriptomics"
]
license https://pasteur.epa.gov/license/sciencehub-license.html
modified 2023-09-08
programCode 
[
  "020:000"
]
publisher 
{
  "name": "U.S. EPA Office of Research and Development (ORD)",
  "subOrganizationOf": {
    "name": "U.S. Environmental Protection Agency",
    "subOrganizationOf": {
      "name": "U.S. Government"
    }
  }
}
references 
[
  "https://doi.org/10.3389/fonc.2024.1389634",
  "https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11099211"
]
rights 
null
title Dataset for "Persistent gene expression and DNA methylation alterations linked to carcinogenic effects of dichloroacetic acid'

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