This digital publication contains the database, base maps, and style files used to build the geologic map of the upper Santa Cruz River basin in southern Arizona published in U.S. Geological Survey Scientific Investigations Map 3490 (Page and others, 2023). Shapefiles are also included for the user’s convenience. In the database, there are polygon features outlining the map units and data sources; line features delineating contacts, faults, and other geologic lines such as dikes, anticlines, and synclines; point features marking where there are age or structural data; and nonspatial tables in which the description of map units, data sources, and glossary information can be found. The database follows the geologic map schema(GeMS) standard format for the digital publication of geologic maps published in U.S. Geological Survey Techniques and Methods 11–B10. The user is directed to the metadata for detailed information on each database component.