This data release supports the study by Sexstone and others (2019) and contains simulation output from a hydrological modeling experiment using a specific calibration of the conterminous United States (CONUS) application of the Precipitation-Runoff Modeling System (PRMS) (Hay, 2019) as implemented in the National Hydrologic Model (NHM) infrastructure (Regan and others, 2018). The by hydrologic response unit (byHRU) calibrated, baseline version of the NHM-PRMS (Hay, 2019) was used to evaluate the sensitivity of simulated runoff to the representation of snow depletion curves (SDCs) within the NHM-PRMS across the CONUS. The model experiment consisted of seven NHM-PRMS model simulations using the calibrated NHM-PRMS model parameters from Hay (2019). For each of the model simulations, the calibrated SDCs (Hay, 2019) were replaced with a single derived SDC derived based on a lognormal probability distribution function and assigned snow water equivalent coefficient of variation (CV) value. The seven CV values ranged from 0.1 to 2.0. Each of the simulations were completed at a daily time-step over a 14-year period (water years 2003 – 2016). Detailed methods and results are provided in Sexstone and others (2019). The SDC parameters used in this model experiment are provided by this data release. Furthermore, the attached NHM-PRMS variable table lists the selected output variables included in this data release. The individual *.csv files follow a naming convention of nhru_variable name_CVX.X.csv. The variable names included are defined further in NHM-PRMS variable table. The “CVX.X” denotes the CV value that was used to derive the SDC for the model simulation. The structure of each output file includes a header line which labels the columns by the HRU identification number with each row providing daily outputs. An inventory of the files provided within this data release can be found below. This research used resources provided by the Core Science Analytics, Synthesis, & Libraries (CSASL) Advanced Research Computing (ARC) group at the U.S. Geological Survey. Inventory of data release: NHM-PRMS_SDC_study.xml (1 .xml file): FGDC-compliant metadata file for the data release files. SDC_params.csv (1 .csv file): Table of the seven snow depletion curve parameterizations used in the modeling study. NHM-PRMS_variable_table.docx (1 .docx file): Table describing the selected NHM-PRMS output variables provided in this data release. nhru_gwres_flow_CVX.X.csv (7 .csv files): NHM-PRMS groundwater discharge output for water years 2002 through 2016. Each of the 7 .csv files are labeled with the coefficient of variation (CV) value for the snow depletion curve that was used in the model simulation. nhru_hru_actet_CVX.X.csv (7 .csv files): NHM-PRMS actual evapotranspiration output for water years 2002 through 2016. Each of the 7 .csv files are labeled with the coefficient of variation (CV) value for the snow depletion curve that was used in the model simulation. nhru_hru_outflow_CVX.X.csv (7 .csv files): NHM-PRMS total flow output for water years 2002 through 2016. Each of the 7 .csv files are labeled with the coefficient of variation (CV) value for the snow depletion curve that was used in the model simulation. nhru_hru_ppt_CVX.X.csv (7 .csv files): NHM-PRMS precipitation output for water years 2002 through 2016. Each of the 7 .csv files are labeled with the coefficient of variation (CV) value for the snow depletion curve that was used in the model simulation. nhru_pkwater_equiv_CVX.X.csv (7 .csv files): NHM-PRMS snow water equivalent output for water years 2002 through 2016. Each of the 7 .csv files are labeled with the coefficient of variation (CV) value for the snow depletion curve that was used in the model simulation. nhru_potet_CVX.X.csv (7 .csv files): NHM-PRMS potential evapotranspiration output for water years 2002 through 2016. Each of the 7 .csv files are labeled with the coefficient of variation (CV) value for the snow depletion curve that was used in the model simulation. nhru_snow_evap_CVX.X.csv (7 .csv files): NHM-PRMS snow sublimation output for water years 2002 through 2016. Each of the 7 .csv files are labeled with the coefficient of variation (CV) value for the snow depletion curve that was used in the model simulation. nhru_snowcov_area_CVX.X.csv (7 .csv files): NHM-PRMS snow covered area output for water years 2002 through 2016. Each of the 7 .csv files are labeled with the coefficient of variation (CV) value for the snow depletion curve that was used in the model simulation. nhru_snowmelt_CVX.X.csv (7 .csv files): NHM-PRMS snowmelt output for water years 2002 through 2016. Each of the 7 .csv files are labeled with the coefficient of variation (CV) value for the snow depletion curve that was used in the model simulation. nhru_sroff_CVX.X.csv (7 .csv files): NHM-PRMS surface runoff output for water years 2002 through 2016. Each of the 7 .csv files are labeled with the coefficient of variation (CV) value for the snow depletion curve that was used in the model simulation. nhru_ssres_flow_CVX.X.csv (7 .csv files): NHM-PRMS interflow output for water years 2002 through 2016. Each of the 7 .csv files are labeled with the coefficient of variation (CV) value for the snow depletion curve that was used in the model simulation. References: Hay, L.E., 2019, Application of the National Hydrologic Model Infrastructure with the Precipitation-Runoff Modeling System (NHM-PRMS), by HRU Calibrated Version: U.S. Geological Survey data release, https://doi.org/10.5066/P9NM8K8W. Regan, R.S., Markstrom, S.L., Hay, L.E., Viger, R.J., Norton, P.A., Driscoll, J.M., LaFontaine, J.H., 2018, Description of the National Hydrologic Model for use with the Precipitation-Runoff Modeling System (PRMS): U.S. Geological Survey Techniques and Methods, book 6, chap. B9, 38 p., accessed May 16, 2018, at https://doi.org/10.3133/tm6B9. Sexstone, G.A., Driscoll, J.M., Hay, L.E., Hammond, J.C., Barnhart T.B., 2019 (in review), Runoff sensitivity to snow depletion curve representation within a continental scale hydrologic model: submitted to Hydrological Processes.