Data from: Expansion of Proteome-wide <i>Coxiella burnetii </i>Comparative T-cell Epitope Prediction to Include Small Ruminant Hosts
Resources
8 resources available
-
Cattle MHC II Non Binder.txt
TXT -
Cattle MHC II Strong Binder.txt
TXT -
Sheep and Goat MHC 1 SB AND WB.txt
TXT -
Sheep and Goat MHC II SB and WB.txt
TXT -
Cattle MHC II Weak Binder.txt
TXT -
Sheep and Goat MHC II Non Binders.txt
TXT -
Goat MHCI Non Binder.txt
TXT -
Sheep MHCI Non Binder.txt
TXT
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Complete Metadata
| @type | dcat:Dataset |
|---|---|
| accessLevel | public |
| bureauCode |
[
"005:18"
]
|
| contactPoint |
{
"fn": "Schneider, David A.",
"hasEmail": "mailto:david.schneider1@usda.gov"
}
|
| description | <p dir="ltr">T-cell epitopes represent sampled environmental- and self-peptides loaded into major histocompatibility complex (MHC) proteins. Bioinformatic tools have been produced to predict these interactions for many species, providing peptides of interest in vaccine development studies.</p><p dir="ltr">Prior work by the researchers (<a href="https://doi.org/10.1186/s12859-021-04181-w" rel="noreferrer" target="_blank">DOI: 10.1186/s12859-021-04181-w</a>) assessed the ability of <i>Coxiella burnetii </i>proteins to interact with MHC alleles in human, mouse, and cattle species, the data from which is available on the Open Science Framework repository with accession number RN6QA (<a href="https://osf.io/rn6qa/" rel="noreferrer" target="_blank">DOI: 10.17605/OSF.IO/RN6QA</a>).</p><p dir="ltr">Presently, bioinformatic programs <a href="https://services.healthtech.dtu.dk/services/NetBoLAIIpan-1.0/" rel="noreferrer" target="_blank">NetBoLAIIpan 1.0</a> and <a href="https://services.healthtech.dtu.dk/services/NetMHCpan-4.1/" target="_blank">NetMHCpan 4.1</a> were employed to predict T-cell epitopes within the <i>C. burnetii </i>proteome for the small ruminant species and to expand cattle predictions. The new datasets available herein provide the species, amino acid sequence, position within the protein, GenBank ID, allele name, and the predicted binding strength for each tested peptide.</p> |
| distribution |
[
{
"@type": "dcat:Distribution",
"title": "Cattle MHC II Non Binder.txt",
"format": "txt",
"mediaType": "text/plain",
"downloadURL": "https://ndownloader.figshare.com/files/43420953"
},
{
"@type": "dcat:Distribution",
"title": "Cattle MHC II Strong Binder.txt",
"format": "txt",
"mediaType": "text/plain",
"downloadURL": "https://ndownloader.figshare.com/files/43421097"
},
{
"@type": "dcat:Distribution",
"title": "Sheep and Goat MHC 1 SB AND WB.txt",
"format": "txt",
"mediaType": "text/plain",
"downloadURL": "https://ndownloader.figshare.com/files/43421112"
},
{
"@type": "dcat:Distribution",
"title": "Sheep and Goat MHC II SB and WB.txt",
"format": "txt",
"mediaType": "text/plain",
"downloadURL": "https://ndownloader.figshare.com/files/43421118"
},
{
"@type": "dcat:Distribution",
"title": "Cattle MHC II Weak Binder.txt",
"format": "txt",
"mediaType": "text/plain",
"downloadURL": "https://ndownloader.figshare.com/files/43421145"
},
{
"@type": "dcat:Distribution",
"title": "Sheep and Goat MHC II Non Binders.txt",
"format": "txt",
"mediaType": "text/plain",
"downloadURL": "https://ndownloader.figshare.com/files/43421148"
},
{
"@type": "dcat:Distribution",
"title": "Goat MHCI Non Binder.txt",
"format": "txt",
"mediaType": "text/plain",
"downloadURL": "https://ndownloader.figshare.com/files/43421151"
},
{
"@type": "dcat:Distribution",
"title": "Sheep MHCI Non Binder.txt",
"format": "txt",
"mediaType": "text/plain",
"downloadURL": "https://ndownloader.figshare.com/files/43421214"
}
]
|
| identifier | 10.15482/USDA.ADC/24712827.v1 |
| keyword |
[
"Coxiella burnetii",
"T-cell epitopes prediction",
"bioinformatics",
"reverse vaccinology",
"small ruminants",
"subunit vaccine targets"
]
|
| license | https://creativecommons.org/publicdomain/zero/1.0/ |
| modified | 2024-07-09 |
| programCode |
[
"005:040"
]
|
| publisher |
{
"name": "Agricultural Research Service",
"@type": "org:Organization"
}
|
| temporal | 2023-02-01/2023-02-01 |
| title | Data from: Expansion of Proteome-wide <i>Coxiella burnetii </i>Comparative T-cell Epitope Prediction to Include Small Ruminant Hosts |
