Data from: Characterizing Host microRNA: Virus Interactions of Orthoavulavirus javaense
This dataset accompanies manuscript "Characterizing Host microRNA: Virus Interactions of Orthoavulavirus javaense" published in the journal Viruses on 11/07/2024. In this manuscript, the authors identified regions in the genome of Orthoavulavirus javaense, the causative of Newcastle disease that can modify function of host microRNAs. They postulate that viral sequences can either mimic host microRNA activity (viral seed mimics) or inhibit (viral seed sponges) it via sequence dependent sequestration. The data suggest that virulent "velogenic" strains of the virus harbor more viral seed mimics vs lentogenic viral genomes that harbor more sponges. The excel file contains tables showing the original BLASTN hits, the shortlisted viral seed mimics and seed sponges and individual tables for viral gene and intergenic region specific hits. The workbook also contains summaries of all the data finally graphed in the manuscript online as well as a list of all accession numbers used in the analysis. The sequences used in these analyses were obtained from NCBI nucleotide and represent full length genomes corresponding to the different pathotypes of NDV.
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Complete Metadata
| @type | dcat:Dataset |
|---|---|
| accessLevel | public |
| accrualPeriodicity | irregular |
| bureauCode |
[
"005:18"
]
|
| contactPoint |
{
"fn": "Bakre Abhijeet A.",
"hasEmail": "mailto:abhijeet.bakre@usda.gov"
}
|
| description | <p dir="ltr">This dataset accompanies manuscript "Characterizing Host microRNA: Virus Interactions of Orthoavulavirus javaense" published in the journal Viruses on 11/07/2024. In this manuscript, the authors identified regions in the genome of Orthoavulavirus javaense, the causative of Newcastle disease that can modify function of host microRNAs. They postulate that viral sequences can either mimic host microRNA activity (viral seed mimics) or inhibit (viral seed sponges) it via sequence dependent sequestration. The data suggest that virulent "velogenic" strains of the virus harbor more viral seed mimics vs lentogenic viral genomes that harbor more sponges. The excel file contains tables showing the original BLASTN hits, the shortlisted viral seed mimics and seed sponges and individual tables for viral gene and intergenic region specific hits. The workbook also contains summaries of all the data finally graphed in the manuscript online as well as a list of all accession numbers used in the analysis. </p><p dir="ltr">The sequences used in these analyses were obtained from NCBI nucleotide and represent full length genomes corresponding to the different pathotypes of NDV. </p> |
| distribution |
[
{
"@type": "dcat:Distribution",
"title": "Supplementary_Tables_vSM-vSS-10-29-2024.xlsx",
"format": "xlsx",
"mediaType": "application/vnd.openxmlformats-officedocument.spreadsheetml.sheet",
"downloadURL": "https://ndownloader.figshare.com/files/50297172"
}
]
|
| identifier | 10.15482/USDA.ADC/27629118.v1 |
| keyword |
[
"MicroRNAs",
"Orthoavulavirus javaense",
"Phosphoprotein",
"Secondary structure",
"Viral seed sponges",
"viral seed mimics"
]
|
| license | https://creativecommons.org/publicdomain/zero/1.0/ |
| modified | 2025-03-06 |
| programCode |
[
"005:040"
]
|
| publisher |
{
"name": "Agricultural Research Service",
"@type": "org:Organization"
}
|
| temporal | 2022-05-01/2024-11-07 |
| title | Data from: Characterizing Host microRNA: Virus Interactions of Orthoavulavirus javaense |
