The Federal Networking and Information Technology Research and Development Program's Middleware and Grid Interagency Coordination Team held a speaker series on containerization and virtualization technologies in Spring 2018. Federal, industry, and academic stakeholders came together to discuss the role of these technologies in supporting scientific workflows involving high-performance computing, high-throughput computing, and cloud computing. The series provided insights into why different fields of science adopted these technologies, how they accomplished the transition, and the challenges they faced. Participants identified the state of the art and discussed the path forward. Scalability, both in terms of code performance and adoption of large-scale computing, was a core focus as the speakers analyzed these innovative frameworks to support multidomain science.