Comparative toxicity of microcystin congeners in mice exposed by the oral route
Physical and serum chemistry effects in mice due to a single oral dose of ten microcystin congeners at a variety of dose levels to determine health effects and a no observable effect level.
This dataset is associated with the following publications:
Chernoff, N. Comparative toxicology of microcystin congeners. U.S. Environmental Protection Agency, Washington, DC, USA.
Chernoff, N., D. Hill, J. Schmid, J. Lang, T. Le, A. Farthing, and H. Huang. The comparative toxicity of ten microcystin congeners administered orally to mice: Clinical effects and organ toxicity.. Toxins. MDPI AG, Basel, SWITZERLAND, 12(6): 403, (2020).
Chernoff, N., D. Hill, J. Schmid, J. Lang, A. Farthing, and H. Huang. Dose-response study of microcystin congeners MCLR, MCLA, MCLY, MCRR, and MCYR administered orally to mice. Toxins. MDPI AG, Basel, SWITZERLAND, 13(2): 86, (2021).
Resources
1 resource available
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MC Congener PO Metadata.xlsx
APPLICATION/VND.OPENXMLFORMATS-OFFICEDOCUMENT.SPREADSHEETML.SHEET
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Complete Metadata
| @type | dcat:Dataset |
|---|---|
| accessLevel | public |
| bureauCode |
[ "020:00" ] |
| contactPoint |
{ "fn": "Neil Chernoff", "hasEmail": "mailto:chernoff.neil@epa.gov" } |
| describedBy | https://pasteur.epa.gov/uploads/10.23719/1519315/documents/Data%20dictionary%20for%20MC%20Congener%20PO%20metadata.docx |
| describedByType | application/vnd.openxmlformats-officedocument.wordprocessingml.document |
| description | Physical and serum chemistry effects in mice due to a single oral dose of ten microcystin congeners at a variety of dose levels to determine health effects and a no observable effect level. This dataset is associated with the following publications: Chernoff, N. Comparative toxicology of microcystin congeners. U.S. Environmental Protection Agency, Washington, DC, USA. Chernoff, N., D. Hill, J. Schmid, J. Lang, T. Le, A. Farthing, and H. Huang. The comparative toxicity of ten microcystin congeners administered orally to mice: Clinical effects and organ toxicity.. Toxins. MDPI AG, Basel, SWITZERLAND, 12(6): 403, (2020). Chernoff, N., D. Hill, J. Schmid, J. Lang, A. Farthing, and H. Huang. Dose-response study of microcystin congeners MCLR, MCLA, MCLY, MCRR, and MCYR administered orally to mice. Toxins. MDPI AG, Basel, SWITZERLAND, 13(2): 86, (2021). |
| distribution |
[ { "title": "MC Congener PO Metadata.xlsx", "mediaType": "application/vnd.openxmlformats-officedocument.spreadsheetml.sheet", "downloadURL": "https://pasteur.epa.gov/uploads/10.23719/1519315/MC%20Congener%20PO%20Metadata.xlsx" } ] |
| identifier | https://doi.org/10.23719/1519315 |
| keyword |
[ "NOAEL", "cyanobacterial toxin", "in vivo data", "microcystins", "toxicology" ] |
| license | https://pasteur.epa.gov/license/sciencehub-license.html |
| modified | 2020-02-20 |
| programCode |
[ "020:096" ] |
| publisher |
{ "name": "U.S. EPA Office of Research and Development (ORD)", "subOrganizationOf": { "name": "U.S. Environmental Protection Agency", "subOrganizationOf": { "name": "U.S. Government" } } } |
| references |
[ "https://doi.org/10.3390/toxins12060403", "https://doi.org/10.3390/toxins13020086" ] |
| rights |
null
|
| title | Comparative toxicity of microcystin congeners in mice exposed by the oral route |
