Wetland restoration efforts conducted by the Coastal Wetlands Planning, Protection and Restoration Act (CWPPRA) in Louisiana rely on monitoring to determine the efficacy of these projects. The Coastwide Reference Monitoring System (CRMS) was developed to assist in a multiple-reference approach that uses aspects of hydrogeomorphic functional assessments and probabilistic sampling for monitoring. The CRMS program includes a suite of approximately 390 sites that encompass the range of hydrological and ecological conditions for each stratum. As part of CRMS, land and water classifications are created from Digital Orthophoto Quarter Quadrangles (DOQQs) approximately every three years at all CRMS sites. This dataset consists of a matrix of six land-water products (2005, 2008, 2012, 2016, 2018, and 2021). The resulting matrix has 64 possible classes defined by the combination of land and water categories on those six dates.