Three different CMIP6-LOCA2 based climate projection data sets are spatially averaged for the contiguous United States using National Park Service administrative units to provide time series for analysis. The primary data set is the statistically downscaled CMIP6-LOCA2 (Localized Constructed Analogs, v20220519 version, Pierce et al. 2023), which includes temperature and precipitation projections from the Climate Model Intercomparison Program Phase 6 (CMIP6) for 27 models under the ssp245, ssp370, and ssp585 scenarios. The “unsplit Livneh” (Pierce et al., 2021) is used as the training data set for LOCA2, where park unit spatial summaries are also included here for convenience. The second data set analyzes the daily LOCA2 to produce 36 annual and 4 monthly threshold and extreme event metrics (CMIP6-LOCA2 Thresholds). Many of the threshold exceedance variables stem from the Climdex project (https://www.climdex.org), which predominately uses metric units. Additional English-based thresholds are included to support Department of the Interior research. The third data set is from a monthly water-balance model that used LOCA2 projections to simulate the hydrological cycle of runoff, snow, soil moisture, and evapotranspiration (CMIP6-LOCA2 MWBM). Users interested in 6 km grids should refer to the home pages of each of the respective sources. Each of these three data sets are spatially average using the National Park Service administrative unit boundaries (included herein as a GeoPackage) and the administrative units intersected with Köppen climate classification for larger park units (also included herein). The NetCDF time series files herein can be linked to the GeoPackage geometries using the “UNIT_CODE” and “PARK_KOPPEN” fields in the respective files.