Challenging Additivity: Comparing Predicted and Observed AhR Activity of PAC Mixtures with Active and Inactive Constituents
EPA-generated data used for basis of modelling in "Challenging Additivity: Comparing Predicted and Observed AhR Activity of PAC Mixtures with Active and Inactive Constituents".
This dataset is associated with the following publication:
Eccles, K., K. Gaston, E. Green, S. Waidyanatha, B. Stiffler, S. Harris, C. Rider, and E. Medlock Kakaley. In vitro assessment of known environmental contaminants and mixtures to determine in vivo relevance. ENVIRONMENT INTERNATIONAL. Elsevier B.V., Amsterdam, NETHERLANDS, 2976-2987, (2026).
Resources
1 resource available
-
Challenging Additivity Manuscript Data_SciHub.xlsx
APPLICATION/VND.OPENXMLFORMATS-OFFICEDOCUMENT.SPREADSHEETML.SHEET
Find Related Datasets
Search by Tags
Click any tag below to search for similar datasets
Complete Metadata
| @type | dcat:Dataset |
|---|---|
| accessLevel | public |
| bureauCode |
[ "020:00" ] |
| contactPoint |
{ "fn": "Elizabeth Medlock Kakaley", "hasEmail": "mailto:medlockkakaley.elizabeth@epa.gov" } |
| description | EPA-generated data used for basis of modelling in "Challenging Additivity: Comparing Predicted and Observed AhR Activity of PAC Mixtures with Active and Inactive Constituents". This dataset is associated with the following publication: Eccles, K., K. Gaston, E. Green, S. Waidyanatha, B. Stiffler, S. Harris, C. Rider, and E. Medlock Kakaley. In vitro assessment of known environmental contaminants and mixtures to determine in vivo relevance. ENVIRONMENT INTERNATIONAL. Elsevier B.V., Amsterdam, NETHERLANDS, 2976-2987, (2026). |
| distribution |
[ { "title": "Challenging Additivity Manuscript Data_SciHub.xlsx", "mediaType": "application/vnd.openxmlformats-officedocument.spreadsheetml.sheet", "downloadURL": "https://pasteur.epa.gov/uploads/10.23719/1532435/Challenging%20Additivity%20Manuscript%20Data_SciHub.xlsx" } ] |
| identifier | https://doi.org/10.23719/1532435 |
| keyword |
[ "Benchmark Concentration", "additivity", "bioassay", "chemical mixtures", "modeling", "potency" ] |
| license | https://pasteur.epa.gov/license/sciencehub-license.html |
| modified | 2025-07-25 |
| programCode |
[ "020:000" ] |
| publisher |
{ "name": "U.S. Environmental Protection Agency", "subOrganizationOf": { "name": "U.S. Government" } } |
| references |
[ "https://doi.org/10.1021/acs.est.5c11914", "https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12874505" ] |
| rights |
null
|
| title | Challenging Additivity: Comparing Predicted and Observed AhR Activity of PAC Mixtures with Active and Inactive Constituents |
