This data release contains inputs and outputs for hydrologic simulations of the conterminous United States (CONUS) using the National Hydrologic Model (NHM) application of the Precipitation Runoff Modeling System (PRMS) in ASCII and binary format and explanatory graphics in pdf format. These simulations were developed to provide estimates of water availability for historical conditions for the period October 1, 1980 to September 30, 2016 for five different calibration configurations; the first three years of the simulation should be considered the initialization period and should not be used for subsequent analysis. The five versions of model parameters and associated model output included in this data release are described in table 1 and in the Supplemental Information section of this metadata record. Table 2 provides information about the baseline datasets used for model calibration for each of the five parameter configurations. Figure 1 shows a schematic of the multi-step calibration procedure used to develop the model parameters. Table 3 describes the 36 model output variables that are included in the five attached folders. Five .tar folders are named according to the simulation configuration in table 1 and include the 36-model output variable files. Table 4 provides information about the 8,274 streamgage locations that are included in the NHM-PRMS. The NHM-PRMS parameter and control files for each of the five simulations are located on the child pages associated with this data release. The PRMS climate forcing input files for the simulations are in the DAYMET_CBH.zip folder. Summary files by streamgage of measured and simulated streamflow for the byHRU, byHRU_musk, and byHRU_musk_obs simulations are in the Streamgage_location_simulations_5999.zip folder. Any time series data in the model output files prior to the October 1, 1983 start date should be considered part of the model initialization period and should not be used. Please refer to the Supplemental Information element of this metadata record for more information about the model calibration, inputs, outputs, and summaries included in this data release.