An examination of the effect of aerosolized Permanone insecticide on zebra finch susceptibility to West Nile virus: Data
Following building an aerosol exposure chamber in which we could expose domesticated zebra finches, we examined the effects of exposure to aerosolized Permanone® 30:30 insecticide (permethrin and piperonyl butoxide in soy oil vehicle) at ~103-106 x potential environmental concentrations on the response to experimental challenge with West Nile virus (WNV). Compared to vehicle control birds, WNV outcome was unchanged (65% of birds produced a viremia) in the ‘low’ exposure (9.52 mg/m3±3.13 SD permethrin) group, but reduced in the ‘high’ exposure (mean 376.5 mg/m3±27.9 SD permethrin) group (30% were viremic) (p < 0.05). After clearing WNV infection, birds treated with Permanone regained less body mass than vehicle treated birds (p < 0.001). Our study suggests that exposure to aerosolized Permanone insecticide at levels exceeding typical application rates has the potential to not change or mildly enhance a bird’s resistance to WNV.
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Complete Metadata
| @type | dcat:Dataset |
|---|---|
| accessLevel | public |
| bureauCode |
[ "010:12" ] |
| contactPoint |
{ "fn": "Erik Hofmeister", "@type": "vcard:Contact", "hasEmail": "mailto:ehofmeister@usgs.gov" } |
| description | Following building an aerosol exposure chamber in which we could expose domesticated zebra finches, we examined the effects of exposure to aerosolized Permanone® 30:30 insecticide (permethrin and piperonyl butoxide in soy oil vehicle) at ~103-106 x potential environmental concentrations on the response to experimental challenge with West Nile virus (WNV). Compared to vehicle control birds, WNV outcome was unchanged (65% of birds produced a viremia) in the ‘low’ exposure (9.52 mg/m3±3.13 SD permethrin) group, but reduced in the ‘high’ exposure (mean 376.5 mg/m3±27.9 SD permethrin) group (30% were viremic) (p < 0.05). After clearing WNV infection, birds treated with Permanone regained less body mass than vehicle treated birds (p < 0.001). Our study suggests that exposure to aerosolized Permanone insecticide at levels exceeding typical application rates has the potential to not change or mildly enhance a bird’s resistance to WNV. |
| distribution |
[ { "@type": "dcat:Distribution", "title": "Digital Data", "format": "XML", "accessURL": "https://doi.org/10.5066/F7TM78KV", "mediaType": "application/http", "description": "Landing page for access to the data" }, { "@type": "dcat:Distribution", "title": "Original Metadata", "format": "XML", "mediaType": "text/xml", "description": "The metadata original format", "downloadURL": "https://data.usgs.gov/datacatalog/metadata/USGS.5a09b689e4b09af898c94770.xml" } ] |
| identifier | http://datainventory.doi.gov/id/dataset/USGS_5a09b689e4b09af898c94770 |
| keyword |
[ "Insecticide", "Laboratory animal model", "Permanone", "USGS:5a09b689e4b09af898c94770", "disease", "pesticide and herbicide contamination", "toxicology" ] |
| modified | 2020-10-16T00:00:00Z |
| publisher |
{ "name": "U.S. Geological Survey", "@type": "org:Organization" } |
| theme |
[ "geospatial" ] |
| title | An examination of the effect of aerosolized Permanone insecticide on zebra finch susceptibility to West Nile virus: Data |
