Skip to main content
U.S. flag

An official website of the United States government

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you’ve safely connected to the .gov website. Share sensitive information only on official, secure websites.

Skip to content
  • Feedback

    • Aggregation of Purified Protein Reference Materials Characterized by Asymmetric Flow Field Flow Fractionation

    Metadata Updated: July 29, 2022

    This is a file containing aggregation data for two proteins that were thermomechanically aggregated. The aggregated proteins were separated by asymmetric flow field flow fractionation and separated protein fractions were detected and quantified by UV spectrophotometry and multi-angle light scattering. The UV spectrophotometry was used to quantify the amount of residual monomer, which is reported herein. The multi-angle light scattering was fitted to a relevant model to calculate the molecular weight of the aggregated protein, also reported herein. The protein aggregation was characterized as a function of time and also the azide (preservative) concentration, which is indicated as being relevant to the aggregation process. The data contained here is plotted in a manuscript submitted to the Journal of Pharmaceutical Sciences and presented as part of that scientific record.

    Access & Use Information

    Public: This dataset is intended for public access and use. License: See this page for license information.

    Downloads & Resources

    Dates

    Metadata Created Date March 11, 2021
    Metadata Updated Date July 29, 2022

    Metadata Source

    Harvested from NIST

    Other Data Resources

    Additional Metadata

    Resource Type Dataset
    Metadata Created Date March 11, 2021
    Metadata Updated Date July 29, 2022
    Publisher National Institute of Standards and Technology
    Maintainer
    Identifier ark:/88434/mds2-2270
    Data First Published 2020-08-21
    Language en
    Data Last Modified 2020-07-23 00:00:00
    Rights https://www.nist.gov/topics/data/public-access-nist-research/copyright-fair-use-and-licensing-statements-srd-data-and
    Category Bioscience:Bioprocessing
    Public Access Level public
    Bureau Code 006:55
    Metadata Context https://project-open-data.cio.gov/v1.1/schema/data.json
    Schema Version https://project-open-data.cio.gov/v1.1/schema
    Catalog Describedby https://project-open-data.cio.gov/v1.1/schema/catalog.json
    Harvest Object Id 09fa0607-7ac2-4320-a420-e1855eb404f7
    Harvest Source Id 74e175d9-66b3-4323-ac98-e2a90eeb93c0
    Harvest Source Title NIST
    Homepage URL https://data.nist.gov/od/id/mds2-2270
    License https://www.nist.gov/open/license
    Program Code 006:045
    Source Datajson Identifier True
    Source Hash 5dd077bbc4cc4476b0eeb7e2f81c022465cda93f
    Source Schema Version 1.1

    Didn't find what you're looking for? Suggest a dataset here.