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    • Acute Ozone-Induced Transcriptional Changes in Markers of Oxidative Stress and Glucocorticoid Signaling in the Rat Hippocampus and Hypothalamus are Sex-Specific

    Metadata Updated: July 2, 2023

    The dataset is comprised of multiple data-frames. Our focus is on sex and brain region specific responses to ozone in a rat model. The PCR data describes the gene expression from listed brain regions resulting from ozone exposure. Complex enzymes were also assayed due to their sensitivity to oxidative stress using biochemical colorimetric assays. And finally, we collected data for oxidative stress artifacts such as protein carbonyl productions, total antioxidants, and enzyme activity.

    This dataset is associated with the following publication: Valdez, M., D. Freeborn, P. Vulimiri, J. Valdez, U. Kodavanti, and P. Kodavanti. Acute Ozone-Induced Transcriptional Changes in Markers of Oxidative Stress and Glucocorticoid Signaling in the Rat Hippocampus and Hypothalamus are Sex-Specific.. International Journal of Molecular Sciences. MDPI, Basel, SWITZERLAND, 24(7): 1, (2023).

    Access & Use Information

    Public: This dataset is intended for public access and use. License: See this page for license information.

    Downloads & Resources

    References

    https://doi.org/10.3390/ijms24076404
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10094823

    Dates

    Metadata Created Date July 2, 2023
    Metadata Updated Date July 2, 2023

    Metadata Source

    Harvested from EPA ScienceHub

    Other Data Resources

    Additional Metadata

    Resource Type Dataset
    Metadata Created Date July 2, 2023
    Metadata Updated Date July 2, 2023
    Publisher U.S. EPA Office of Research and Development (ORD)
    Maintainer
    Identifier https://doi.org/10.23719/1528538
    Data Last Modified 2023-02-01
    Public Access Level public
    Bureau Code 020:00
    Schema Version https://project-open-data.cio.gov/v1.1/schema
    Data Dictionary https://pasteur.epa.gov/uploads/10.23719/1528538/documents/datadictionary_MFO3.xlsx
    Data Dictionary Type application/vnd.openxmlformats-officedocument.spreadsheetml.sheet
    Harvest Object Id ba156e31-d077-40fd-b941-e1c45b37150a
    Harvest Source Id 04b59eaf-ae53-4066-93db-80f2ed0df446
    Harvest Source Title EPA ScienceHub
    License https://pasteur.epa.gov/license/sciencehub-license.html
    Program Code 020:000
    Publisher Hierarchy U.S. Government > U.S. Environmental Protection Agency > U.S. EPA Office of Research and Development (ORD)
    Related Documents https://doi.org/10.3390/ijms24076404, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10094823
    Source Datajson Identifier True
    Source Hash 1f749a55911ac1096cac10de8dbdae314dbe64cd
    Source Schema Version 1.1

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