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    • A study of gene expression influenced by simulated microgravity in human lymphoblastoid cells

    Metadata Updated: April 24, 2025

    Here in this study we systematically examined the patterns of DNA methylation and hydroxy-methylation with its functional implications in gene regulation for the cultured TK6 lymphoblastoid cells upon exposure to micro-gravity conditions. The results reported here indicate that simulated microgravity alters methylation patterns in a limited way and subsequently the expression of genes involved in stress response like ATF3 FBXO17 MAP3K13 and VCL in TK6 cells. Overall design: Examination of RNA-seq with 2 replicates each for 1 cell type

    Access & Use Information

    Public: This dataset is intended for public access and use. License: No license information was provided. If this work was prepared by an officer or employee of the United States government as part of that person's official duties it is considered a U.S. Government Work.

    Downloads & Resources

    Dates

    Metadata Created Date January 31, 2023
    Metadata Updated Date April 24, 2025
    Data Update Frequency irregular

    Metadata Source

    Harvested from NASA Data.json

    Other Data Resources

    Additional Metadata

    Resource Type Dataset
    Metadata Created Date January 31, 2023
    Metadata Updated Date April 24, 2025
    Publisher National Aeronautics and Space Administration
    Maintainer
    Identifier nasa_genelab_GLDS-91_bjtj-w8rd
    Data First Published 2018-06-26
    Data Last Modified 2025-04-23
    Category Earth Science
    Public Access Level public
    Data Update Frequency irregular
    Bureau Code 026:00
    Metadata Context https://project-open-data.cio.gov/v1.1/schema/catalog.jsonld
    Schema Version https://project-open-data.cio.gov/v1.1/schema
    Catalog Describedby https://project-open-data.cio.gov/v1.1/schema/catalog.json
    Harvest Object Id ef73be74-86a4-47b0-b1b1-48dcb0448cf4
    Harvest Source Id 58f92550-7a01-4f00-b1b2-8dc953bd598f
    Harvest Source Title NASA Data.json
    Homepage URL https://data.nasa.gov/dataset/a-study-of-gene-expression-influenced-by-simulated-microgravity-in-human-lymphoblastoid-ce
    Program Code 026:005
    Source Datajson Identifier True
    Source Hash 1461996eeba946a2e815ad804fc9080f6cf99ac42d8ab36dcc9619809aff8793
    Source Schema Version 1.1

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