-
Federal
Transient gene expression profile changes of confluent human fibroblast cells in spaceflight recent views
National Aeronautics and Space Administration —
Microgravity or an altered gravity environment from the static 1g has been shown to influence global gene expression patterns and protein levels in cultured cells or... -
Federal
Gene-expression profiling of Saccharomyces cerevisiae irradiated by high-LET radiations recent views
National Aeronautics and Space Administration —
Ionizing radiations are categorized by linear energy transfer (LET) into low-LET and high-LET. High-LET is considered to have a higher relative biological... -
Federal
Transcription profiling of rat keratinocytes exposed to a 56Fe ion beam recent views
National Aeronautics and Space Administration —
The purpose of the present work was to examine gene expression patterns in a rat keratinocyte line exposed to a 56Fe ion beam Experiment Overall Design: The cells... -
Federal
Evaluation of in vitro macrophage differentiation during space flight recent views
National Aeronautics and Space Administration —
We differentiated mouse bone marrow cells in the presence of recombinant macrophage colony stimulating (rM-CSF) factor for 14 days during the flight of space shuttle... -
Federal
Spaceflight effects on the mouse retina: Histological gene expression and epigenetic changes after flight on STS-135 recent views
National Aeronautics and Space Administration —
We report the findings of an animal experiment onboard STS-135 investigating the molecular aspects of the impact of spaceflight on retinal biology by performing... -
Federal
mRNA expression profile in DLD-1 and MOLT-4 cancer cell lines cultured under Microgravity recent views
National Aeronautics and Space Administration —
DLD-1 and MOLT-4 cell lines were cultured in a rotating cell culture system to simulate microgravity and mRNA expression profile in comparison to Static controls.... -
Federal
Effect of acute muscle unloading on soleus and gastrocnemius muscle gene expression recent views
National Aeronautics and Space Administration —
Gene expression changes induced by acute skeletal muscle unloading which leads to physiological changes including muscle atrophy fibre-type switching and loss of... -
Federal
Dissecting Low Atmospheric Pressure Stress: Transcriptome Responses to the Components of Hypobaria in Arabidopsis [Experiment 2] recent views
National Aeronautics and Space Administration —
Controlled hypobaria presents biology with an environment that is never encountered in terrestrial ecology yet the apparent components of hypobaria are stresses... -
Federal
Comparative gene expression analysis in the Arabidopsis thaliana root apex using RNA-seq and microarray transcriptome profiles recent views
National Aeronautics and Space Administration —
The root apex is an important section of the plant root involved in environmental sensing and cellular development. Analyzing the gene profile of root apex in diverse... -
Federal
Delayed Cardiomyocyte Response to Total Body Particle Radiation Exposure - Identification of Regulatory Gene Network [proton] recent views
National Aeronautics and Space Administration —
We examined molecular responses using transcriptome profiling in isolated left ventricular murine cardiomyocytes to 90 cGy 1 GeV proton (1H) and 15 cGy 1 GeV/nucleon... -
Federal
Global Identification of Noncoding RNAs in S. cerevisiae recent views
National Aeronautics and Space Administration —
Genome-wide detection of novel non-coding RNAs in S. cerevisiae by modulating an RNase P pathway through the depletion of a component RPP1. Nearly 400,000 36-mer... -
Federal
Response of the EPI-200 human 3-D skin model to high and low doses of protons recent views
National Aeronautics and Space Administration —
Accumulating data suggest that the biological responses to high and low doses of radiation are qualitatively different necessitating the direct study of low dose... -
Federal
Osteocytes transcriptome is altered during spaceflight recent views
National Aeronautics and Space Administration —
Bone loss is one of the major health problems for astronauts during long-term spaceflight and for patients during prolonged bed rest or paralysis. Growing evidence... -
Federal
Global gene expression analysis highlights microgravity sensitive key genes in soleus and EDL of 30 days space flown mice recent views
National Aeronautics and Space Administration —
Microgravity exposure as well as chronic muscle disuse are two of the main causes of physiological adaptive skeletal muscle atrophy in humans and murine animals in... -
Federal
Evaluation of in vitro macrophage differentiation during space flight recent views
National Aeronautics and Space Administration —
We differentiated mouse bone marrow cells in the presence of recombinant macrophage colony stimulating (rM-CSF) factor for 14 days during the flight of space shuttle... -
Federal
Effects of spaceflight on murine skeletal muscle gene expression recent views
National Aeronautics and Space Administration —
Spaceflight results in a number of adaptations to skeletal muscle including atrophy and shifts towards faster muscle fiber types. To identify changes in gene... -
Federal
Global gene expression profiling of radiation-induced rat mammary carcinomas recent views
National Aeronautics and Space Administration —
To investigate gene expression patterns in rat mammary carcinomas induced by ionizing radiation. Gene expression patterns were analyzed in radiation-induced rat... -
Federal
Global gene expression analysis highlights microgravity sensitive key genes in longissimus dorsi and tongue of 30 days space-flown mice recent views
National Aeronautics and Space Administration —
Microgravity as well as chronic muscle disuse are two causes of low back pain originated at least in part from paraspinal muscle deconditioning. At present no study... -
Federal
Gene-expression profiling of Saccharomyces cerevisiae irradiated by high-LET radiations recent views
National Aeronautics and Space Administration —
Ionizing radiations are categorized by linear energy transfer (LET) into low-LET and high-LET. High-LET is considered to have a higher relative biological... -
Federal
Response of the EPI-200 human 3-D skin model to high and low doses of protons recent views
National Aeronautics and Space Administration —
Accumulating data suggest that the biological responses to high and low doses of radiation are qualitatively different necessitating the direct study of low dose...