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Federal
Dynamic gene expression response to altered gravity in human T cells (sounding rocket flight) recent views
National Aeronautics and Space Administration —
We investigated differentially regulated genes in human Jurkat T lymphocytic cells in 20s and 5min microgravity and in hypergravity and compared expression profiles... -
Federal
Transcription profiling of rat keratinocytes exposed to a 56Fe ion beam recent views
National Aeronautics and Space Administration —
The purpose of the present work was to examine gene expression patterns in a rat keratinocyte line exposed to a 56Fe ion beam Experiment Overall Design: The cells... -
Federal
Effect of acute muscle unloading on soleus and gastrocnemius muscle gene expression recent views
National Aeronautics and Space Administration —
Gene expression changes induced by acute skeletal muscle unloading which leads to physiological changes including muscle atrophy fibre-type switching and loss of... -
Federal
Zebrafish larvae submitted to simulated microgravity on a clinostat (CLINO) at 5dpf for one day recent views
National Aeronautics and Space Administration —
The general objective of the study was to determine modulation of gene expression by environmental factors specifically simulation of microgravity with a special... -
Federal
Dissecting Low Atmospheric Pressure Stress: Transcriptome Responses to the Components of Hypobaria in Arabidopsis [Experiment 2] recent views
National Aeronautics and Space Administration —
Controlled hypobaria presents biology with an environment that is never encountered in terrestrial ecology yet the apparent components of hypobaria are stresses... -
Federal
The Heat-Inducible Transcription Factor HsfA2 Enhances Anoxia Tolerance in Arabidopsis recent views
National Aeronautics and Space Administration —
Anoxia induces several heat shock proteins and a heat pre-treatment can acclimatize Arabidopsis seedlings to a subsequent anoxic treatment. In this work we analyzed... -
Federal
Expression data from rice calli cultured with 2,4-D recent views
National Aeronautics and Space Administration —
Four days old rice calli were selected to grow 324h under spaceflight controls 1g-flight controls and 1g-ground controls. We used microarrays to detail the global... -
Federal
Effects of a Closed Space Environment on Gene Expression in Hair Follicles of Astronauts in the International Space Station recent views
National Aeronautics and Space Administration —
In recent times long-term stay has become a common occurrence in the International Space Station (ISS). However adaptation to the space environment can sometimes pose... -
Federal
Response of the EPI-200 human 3-D skin model to high and low doses of protons recent views
National Aeronautics and Space Administration —
Accumulating data suggest that the biological responses to high and low doses of radiation are qualitatively different necessitating the direct study of low dose... -
Federal
Osteocytes transcriptome is altered during spaceflight recent views
National Aeronautics and Space Administration —
Bone loss is one of the major health problems for astronauts during long-term spaceflight and for patients during prolonged bed rest or paralysis. Growing evidence... -
Federal
Evaluation of in vitro macrophage differentiation during space flight recent views
National Aeronautics and Space Administration —
We differentiated mouse bone marrow cells in the presence of recombinant macrophage colony stimulating (rM-CSF) factor for 14 days during the flight of space shuttle... -
Federal
Dynamic gene expression response to altered gravity in human T cells (parabolic flight) recent views
National Aeronautics and Space Administration —
We investigated differentially regulated genes in human Jurkat T lymphocytic cells in 20s and 5min microgravity and in hypergravity and compared expression profiles... -
Federal
Zebrafish larvae submitted to simulated microgravity on a clinostat (CLINO) at 5dpf for one day recent views
National Aeronautics and Space Administration —
The general objective of the study was to determine modulation of gene expression by environmental factors specifically simulation of microgravity with a special... -
Federal
Dynamic gene expression response to altered gravity in human T cells (parabolic flight) recent views
National Aeronautics and Space Administration —
We investigated differentially regulated genes in human Jurkat T lymphocytic cells in 20s and 5min microgravity and in hypergravity and compared expression profiles... -
Federal
The response of murine cartilages to 30 days of microgravity recent views
National Aeronautics and Space Administration —
Articular and sterno-costal cartilages were isolated from skeletally-mature mice flown for 30 days on the BION-M1 mission. Samples were characterized histologically... -
Federal
Global gene expression profiling of radiation-induced rat mammary carcinomas recent views
National Aeronautics and Space Administration —
To investigate gene expression patterns in rat mammary carcinomas induced by ionizing radiation. Gene expression patterns were analyzed in radiation-induced rat... -
Federal
Arg1 functions in the physiological adaptation of undifferentiated plant cells to spaceflight recent views
National Aeronautics and Space Administration —
In this study transcriptome profiling was used to gain insight into the spaceflight adaptation role of Altered response to gravity-1 (Arg1) a gene known to affect... -
Federal
Effects of spaceflight on murine skeletal muscle gene expression recent views
National Aeronautics and Space Administration —
Spaceflight results in a number of adaptations to skeletal muscle including atrophy and shifts towards faster muscle fiber types. To identify changes in gene... -
Federal
Gamma radiation and HZE treatment of seedlings in Arabidopsis recent views
National Aeronautics and Space Administration —
Plants exhibit a robust transcriptional response to gamma radiation which includes the induction of transcripts required for homologous recombination and the... -
Federal
Transcription profiling of mouse osteoblasts under static vs simulated microgravity recent views
National Aeronautics and Space Administration —
The total RNA was extracted from 2T3 pre-osteoblast cells exposed to static or simulated microgravity (Rotating Wall Vessel) conditions. The RNA was then sent to...