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Federal
Microbiome profiling of feces from mice flown on the RR-10 mission
National Aeronautics and Space Administration —
The objective of the Rodent Research-10 Mission (RR-10) was to investigate how spaceflight affects the cellular and molecular mechanisms of normal bone tissue... -
Federal
Influence of gonadectomy on muscle health in micro- and partial-gravity environments in rats (Grip; force transducer)
National Aeronautics and Space Administration —
Gonadal hormones, such as testosterone and estradiol, modulate muscle size and strength in males and females. However, the influence of sex hormones on muscle... -
Federal
Effects of 5-Ion Beam Irradiation and Hindlimb Unloading on Metabolic Pathways in Plasma and Brain of Behaviorally Tested WAG/Rij Rats
National Aeronautics and Space Administration —
A limitation of simulated space radiation studies is that radiation exposure is not the only environmental challenge astronauts face during missions. Therefore, we... -
Federal
Spaceflight Modulates Gene Expression in Astronauts
National Aeronautics and Space Administration —
Astronauts are exposed to a unique combination of stressors during spaceflight, which leads to alterations in their physiology and potentially increases their... -
Federal
Transcriptional analysis of dorsal skin from mice flown on the RR-6 mission
National Aeronautics and Space Administration —
The objective of the Rodent Research-6 (RR-6) study was to evaluate muscle atrophy in mice during spaceflight and to test the efficacy of a novel therapeutic to... -
Federal
Heart Flies - effect of microgravity on heart function in Drosophila
National Aeronautics and Space Administration —
Canton S laboratory wildtype lines (Bloomington Stock Center) and a K+ channel mutant seizure (seizurets1, a gift from Dr. Barry Ganetsky, published in Titus et al.,... -
Federal
Targeting myostatin/activin A protects against skeletal muscle and bone loss during spaceflight [plasma proteomics]
National Aeronautics and Space Administration —
Among the physiological consequences of extended spaceflight are loss of skeletal muscle and bone mass. One signaling pathway that plays an important role in... -
Federal
Single-molecule long-read methylation profiling reveals regional DNA methylation regulated by Elongator Complex Subunit 2 in Arabidopsis roots experiencing spaceflight
National Aeronautics and Space Administration —
The Advanced Plant Experiment-04 - Epigenetic Expression (APEX-04-EpEx) experiment onboard the International Space Station examined the spaceflight-altered cytosine... -
Federal
The impact of deep space radiation on cognitive performance: From biological sex to biomarkers to countermeasures (Flow Cytometry, Synapse from Hippocampus)
National Aeronautics and Space Administration —
In the coming decade, astronauts will travel back to the moon in preparation for future Mars missions. Exposure to galactic cosmic radiation (GCR) is a major obstacle... -
Federal
Head-Down Tilt As a Model for Intracranial and Intraocular Pressures, and Retinal Changes during Spaceflight (Eye, MRI, Optical Coherence Tomography, Tonometry, A-scan)
National Aeronautics and Space Administration —
This ground-based program was intended to address the etiology of visual system structural and functional changes observed in astronauts during both inflight and... -
Federal
Metagenomic analysis of feces from mice flown on the RR-9 mission
National Aeronautics and Space Administration —
The objective of the Rodent Research-9 (RR-9) mission was to use mice to understand the molecular basis of phenomena that affect astronauts during long-duration... -
Federal
Transcriptional profiling of right quadriceps femoris muscle from mice flown on the RR-23 mission
National Aeronautics and Space Administration —
The objective of the Rodent Research-23 mission (RR-23) was to better understand the effects of spaceflight on the eyes, specifically on the structure and function of... -
Federal
Genomic Characterization and Virulence Potential of Two Fusarium oxysporum Isolates Cultured from the International Space Station
National Aeronautics and Space Administration —
Two isolates of Fusarium oxysporum, ISS-F3 and ISS-F4, were cultured from the dining table on the International Space Station (ISS). Genomic analyses using EF-1α... -
Federal
Effects of Space Flight on Inflammasome Activation in the Brain of Mice (Brain, Western Blot and ECLIA)
National Aeronautics and Space Administration —
Space exploration exposes astronauts to stressors that alter the immune response, rendering them vulnerable to infections and diseases. In this study, we aimed to... -
Federal
Fungal Diversity associated with space-craft assembly facility (SAF)
National Aeronautics and Space Administration —
Draft genome sequences of Fungi isolated from Mars 2020 Spacecraft assembly facility are reported. The fungal strains were isolated from samples collected from... -
Federal
Characterization of mouse ocular response to a 35-day spaceflight mission: Evidence of blood-retinal barrier disruption and ocular adaptations - Proteomics data
National Aeronautics and Space Administration —
The health risks associated with spaceflight-induced ocular structural and functional damage has become a recent concern for NASA. The goal of the present study was... -
Federal
International Space Station - Microbial Observatory of Pathogenic Virus, Bacteria, and Fungi project
National Aeronautics and Space Administration —
This study investigated the interplay between the microbial community of the International Space Station and its crew. Environmental samples were collected from 8... -
Federal
Apollo 17 Challenge System - Seed Germination (Cabbage, Brussel Sprouts, Radish and Lettuce)
National Aeronautics and Space Administration —
Analyses of effects of lunar materials on plants: This study was designed to determine if lunar material can cause disease in plants grown under controlled conditions... -
Federal
Exposure to elevated relative humidity in laboratory chambers alters fungal gene expression in dust from the International Space Station (ISS)
National Aeronautics and Space Administration —
Microbes are present in all occupied indoor environments, including the International Space Station (ISS). An unexpected ventilation system failure may lead to... -
Federal
Effect of varying amounts of simulated lunar soil batch #005 upon growth of lettuce explants
National Aeronautics and Space Administration —
The following general conclusions can be made concerning the use of tissue culture for assaying the effects of mineral elements from simulated lunar soil or other...