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Federal
Plant Gravity Perception: Pilot (PGP Pilot)
National Aeronautics and Space Administration —
This study examined tissue-specific early transcriptional responses upon reorientation in wild type and starchless pgm-1 mutant seedlings of Arabidopsis. Seedlings... -
Federal
The International Space Station Has a Unique and Extreme Microbial and Chemical Environment Driven by Use Patterns
National Aeronautics and Space Administration —
Space habitation provides unique challenges in built environments isolated from Earth. We produced a 3D map of the microbes and metabolites throughout the... -
Federal
Comprehensive multi-omics analysis reveals mitochondrial stress as a central biological hub for spaceflight impact
National Aeronautics and Space Administration —
Given the limited knowledge of the biological impact of spaceflight, a multi-omics, systems biology approach was used to investigate NASA’s GeneLab data and astronaut... -
Federal
Microbiome profiling of feces from mice flown on the RR-10 mission
National Aeronautics and Space Administration —
The objective of the Rodent Research-10 Mission (RR-10) was to investigate how spaceflight affects the cellular and molecular mechanisms of normal bone tissue... -
Federal
Effect of varying amounts of simulated lunar soil batch #005 upon growth of lettuce explants
National Aeronautics and Space Administration —
The following general conclusions can be made concerning the use of tissue culture for assaying the effects of mineral elements from simulated lunar soil or other... -
Federal
Long-read sequencing reveals increased occurrence of genomic variants and adenosine methylation in Bacillus pumilus SAFR-032 after long-duration flight exposure onboard the International Space Station
National Aeronautics and Space Administration —
Bacillus pumilus SAFR-032, an endospore-forming bacterial strain, was investigated to determine its methylation pattern (methylome) change, compared to ground... -
Federal
Transcriptional profiling of thymus from mice flown on the RR-9 mission
National Aeronautics and Space Administration —
The objective of the Rodent Research-9 (RR-9) mission was to use mice to understand the molecular basis of phenomena that affect astronauts during long-duration... -
Federal
Fifteen days of microgravity causes growth in calvaria of mice (STS-131)
National Aeronautics and Space Administration —
Bone growth may occur in spaceflight as a response to skeletal unloading and head-ward fluid shifts. While unloading causes significant loss of bone mass and density... -
Federal
Characterizing Epigenetic Changes in Methylation Mutants (elp2-5 and met1-7) in Response to Spaceflight. [RNA-Seq]
National Aeronautics and Space Administration —
Epigenetic changes in the DNA methylome are increasingly shown to play an integral role in regulating gene expression necessary for plants adaption to environmental... -
Federal
STS-135 Cerebellum Transcriptomics
National Aeronautics and Space Administration —
Mice were flown onboard STS-135 and returned to Earth for analysis. Cerebellums were collected within 3-4 hours of landing and snap frozen in liquid nitrogen. Samples... -
Federal
The impact of deep space radiation on cognitive performance: From biological sex to biomarkers to countermeasures (Elevated Plus Maze, Novel Object Recognition, Open Field, Radial Arm Water Maze, and Three Chamber Social Isolation/Interaction)
National Aeronautics and Space Administration —
In the coming decade, astronauts will travel back to the moon in preparation for future Mars missions. Exposure to galactic cosmic radiation (GCR) is a major obstacle... -
Federal
BRIC-23 GeneLab Process Verification Test: Staphylococcus aureus transcriptomic, proteomic, and metabolomic data
National Aeronautics and Space Administration —
Microbes interact with humans in complex ways and understanding how they respond to the spaceflight environment is important to the success of future manned... -
Federal
Bulk RNA sequencing and spatially resolved transcriptional profiling of cerebellums from mice flown on the RR-10 mission
National Aeronautics and Space Administration —
The objective of the Rodent Research-10 mission (RR-10) was to investigate how spaceflight affects the cellular and molecular mechanisms of normal bone tissue... -
Federal
Microbiological and nutritional analysis of lettuce crops grown on the International Space Station-VEG01A
National Aeronautics and Space Administration —
The ability to grow safe, fresh food to supplement packaged foods of astronauts in space has been an important goal for NASA. Food crops grown in space experience... -
Federal
Alternative splicing regulates the physiological adaptation of the mouse hind limb postural and phasic muscles to microgravity
National Aeronautics and Space Administration —
We sought to comprehensively elucidate the transcriptomic underpinnings of microgravity-induced muscle phenotypes in mice by evaluating both differential gene... -
Federal
Transcriptional profiling of thymus from mice flown on the RR-23 mission
National Aeronautics and Space Administration —
The objective of the Rodent Research-23 missions (RR-23) was to better understand the effects of spaceflight on the eyes, specifically on the structure and function... -
Federal
Spatial characterization of microbial communities on multi-species leafy greens grown simultaneously in the Veggie vegetable production systems on the International Space Station VEG-03D
National Aeronautics and Space Administration —
Investigates the microbial communities of plants and Veggie pillow components with culturable and non-culturable methods providing qualitative and quantitative data.... -
Federal
Response of human lymphoblastoid cells to HZE (iron ions) or gamma-rays
National Aeronautics and Space Administration —
Transcriptional profiling of human lymphoblastoid TK6 cells comparing mock irradiated cells with cells exposed 24 hours previously to 1.67 Gy HZE (1 GeV/amu iron ions... -
Federal
Correlated Gene and Protein Expression in heads from Drosophila reared in microgravity
National Aeronautics and Space Administration —
Omics analyses of RNA and protein isolated from heads of microgravity reared adult Drosophila.