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Federal
The genetic structure of recombinant inbred mice: high-resolution consensus maps for complex trait analysis
U.S. Department of Health & Human Services —
Background Recombinant inbred (RI) strains of mice are an important resource used to map and analyze complex traits. They have proved particularly effective in... -
Federal
Oral contraceptive use before first birth and risk of breast cancer: a case control study
U.S. Department of Health & Human Services —
Background The aim of this study was first, to investigate whether women starting oral contraceptive (OC) use at a young age and before first birth have an increased... -
Federal
Change of dopamine receptor mRNA expression in lymphocyte of schizophrenic patients
U.S. Department of Health & Human Services —
Background Though the dysfunction of central dopaminergic system has been proposed, the etiology or pathogenesis of schizophrenia is still uncertain partly due to... -
Federal
Pulse pressure and age at menopause
U.S. Department of Health & Human Services —
Background The objective of this study was to study the association of early age at menopause with pulse pressure (PP), a marker of arterial stiffness, and PP change.... -
Federal
The influence of age on the female/male ratio of treated incidence rates in depression
U.S. Department of Health & Human Services —
Background Poor data exist on the influence of psychosocial variables on the female/male ratio of depression because of the small number of cases and the resulting... -
Federal
Auto-protective redox buffering systems in stimulated macrophages
U.S. Department of Health & Human Services —
Background Macrophages, upon encounter with micro-organisms or stimulated by cytokines, produce various effector molecules aimed at destroying the foreign agents and... -
Federal
Recruitment, augmentation and apoptosis of rat osteoclasts in 1,25-(OH)
U.S. Department of Health & Human Services —
Background Although much is known about the regulation of osteoclast (OC) formation and activity, little is known about OC senescence. In particular, the fate of of... -
Federal
Accessing and distributing EMBL data using CORBA (common object request broker architecture)
U.S. Department of Health & Human Services —
Background: The EMBL Nucleotide Sequence Database is a comprehensive database of DNA and RNA sequences and related information traditionally made available in flat-... -
Federal
Expression of monolysocardiolipin acyltransferase activity is regulated in concert with the level of cardiolipin and cardiolipin biosynthesis in the mammalian heart
U.S. Department of Health & Human Services —
Background Monolysocardiolipin acyltransferase (MLCL AT) catalyzes the acylation of monolysocardiolipin to cardiolipin in mammalian tissues. We previously reported... -
Federal
Ibuprofen 400 mg is effective in women, and women are well represented in trials
U.S. Department of Health & Human Services —
Background A recent article in the New Scientist argued that women were under-represented in clinical trials which, until now, had masked the finding that ibuprofen... -
Federal
Impact of obesity on glucose and lipid profiles in adolescents at different age groups in relation to adulthood
U.S. Department of Health & Human Services —
Background As obesity is rapidly becoming a major medical and public health problem, the aim of our study was to determine: 1) if obesity in Caucasian adolescents at... -
Federal
Identification and preliminary characterization of mouse
U.S. Department of Health & Human Services —
Background The metalloprotease-disintegrin family, or ADAM, proteins, are implicated in cell-cell interactions, cell fusion, and cell signaling, and are widely... -
Federal
Survey of transcripts in the adult
U.S. Department of Health & Human Services —
Background: Classic methods of identifying genes involved in neural function include the laborious process of behavioral screening of mutagenized flies and then... -
Federal
Chromosomal mapping, gene structure and characterization of the human and murine
U.S. Department of Health & Human Services —
Background Rab GTPases are regulators of intracellular membrane traffic. The Rab27 subfamily consists of Rab27a and Rab27b. Rab27a has been recently implicated in... -
Federal
Clinical ethics revisited
U.S. Department of Health & Human Services —
A decade ago, we reviewed the field of clinical ethics; assessed its progress in research, education, and ethics committees and consultation; and made predictions... -
Federal
Problems in dealing with missing data and informative censoring in clinical trials
U.S. Department of Health & Human Services —
A common problem in clinical trials is the missing data that occurs when patients do not complete the study and drop out without further measurements. Missing data... -
Federal
Colonic tuberculosis mimicking Crohn's disease: case report
U.S. Department of Health & Human Services —
Background Intestinal tuberculosis is a rare disease in western countries, affecting mainly immigrants and immunocompromised patients. Intestinal tuberculosis is a... -
Federal
Method for non-invasively recording electrocardiograms in conscious mice
U.S. Department of Health & Human Services —
Background The rapid increase in the development of mouse models is resulting in a growing demand for non-invasive physiological monitoring of large quantities of... -
Federal
Red blood cell transfusion does not increase oxygen consumption in critically ill septic patients
U.S. Department of Health & Human Services —
Background Red blood cell (RBC) transfusion is commonly used to increase oxygen transport in patients with sepsis. However it does not consistently increase oxygen... -
Federal
Apolipoprotein C3 SstI polymorphism and triglyceride levels in Asian Indians
U.S. Department of Health & Human Services —
Background A close association between Sst I polymorphism in the 3' untranslated region of the apolipoproteinC3 (APOC3) gene and levels of plasma triglycerides (TG)...