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Federal
Intestinal parasitic infections in Thai HIV-infected patients with different immunity status
U.S. Department of Health & Human Services —
Background One of the major health problems among HIV seropositive patients is superimposed infection due to the defect of immunity. Furthermore, intestinal parasite... -
Federal
Th2 cytokines and asthma: an introduction
U.S. Department of Health & Human Services —
Th2 cytokines and asthma: an introduction -
Federal
Toll-like receptors: the key to the stable door?
U.S. Department of Health & Human Services —
Severe sepsis continues to lead to critical illness. Few therapeutic options exist other than antibiotic therapy and general supportive care. Large numbers of... -
Federal
Autologous stem-cell transplantation in refractory autoimmune diseases after
U.S. Department of Health & Human Services —
Autoimmune diseases that are resistant to conventional treatment cause severe morbidity and even mortality. In the present study we demonstrate that complete... -
Federal
MHC class I multimers
U.S. Department of Health & Human Services —
T lymphocytes play a key role in the immune response to both foreign and self peptide antigens, which they recognize in combination with MHC molecules. In the past it... -
Federal
Importance of lysosomal cysteine proteases in lung disease
U.S. Department of Health & Human Services —
The human lysosomal cysteine proteases are a family of 11 proteases whose members include cathepsins B, C, H, L, and S. The biology of these proteases was largely... -
Federal
Post-transcriptional regulation of pro-inflammatory gene expression
U.S. Department of Health & Human Services —
The cytokine tumour necrosis factor (TNF)α is a vital mediator of the innate immune response, and a pleiotropic regulator of cellular function. Its involvement in... -
Federal
Viruses, dendritic cells and the lung
U.S. Department of Health & Human Services —
The interaction between viruses and dendritic cells (DCs) is varied and complex. DCs are key elements in the development of a host response to pathogens such as... -
Federal
Decreased inducibility of TNF expression in lipid-loaded macrophages
U.S. Department of Health & Human Services —
Background Inflammation and immune responses are considered to be very important in the pathogenesis of atherosclerosis. Lipid accumulation in macrophages of the... -
Federal
Cell-cell interactions in synovitis: Endothelial cells and immune cell migration
U.S. Department of Health & Human Services —
Leukocyte ingress into the synovium is a key process in the pathogenesis of rheumatoid arthritis and other inflammatory conditions. In this review, the role of... -
Federal
Low-volume jet injection for intradermal immunization in rabbits
U.S. Department of Health & Human Services —
Background This study tested a low-volume (20–30 μl/20–30 μg DNA) jet injection method for intradermal delivery of a DNA vaccine. Jet injection offers the advantages... -
Federal
Age-dependent changes in 24-hour rhythms of catecholamine content and turnover in hypothalamus, corpus striatum and pituitary gland of rats injected with Freund's adjuvant
U.S. Department of Health & Human Services —
Background Little information is available on the circadian sequela of an immune challenge in the brain of aged rats. To assess them, we studied 24-hour rhythms in... -
Federal
Enhanced immunogenicity of a functional enzyme by T cell epitope modification
U.S. Department of Health & Human Services —
Background T helper epitopes are necessary for the induction of high titers of antigen-specific IgG antibodies. We are interested in the epitope modification of... -
Federal
Joint disease caused by defective gp130-mediated STAT signaling
U.S. Department of Health & Human Services —
IL-6 is a multifunctional cytokine produced by lymphoid and nonlymphoid cells; it regulates immune responses, acute-phase reactions, and inflammation. IL-6 signaling... -
Federal
Cell-cell interactions in synovitis: Interactions between T cells and B cells in rheumatoid arthritis
U.S. Department of Health & Human Services —
In rheumatoid arthritis, T cells and B cells participate in the immune responses evolving in the synovial lesions. Interaction between T cells and B cells is probably... -
Federal
Expression of cytokine and chemokine mRNA and secretion of tumor necrosis factor-α by gallbladder epithelial cells: Response to bacterial lipopolysaccharides
U.S. Department of Health & Human Services —
Background In addition to immune cells, many other cell types are known to produce cytokines. Cultured normal mouse gallbladder epithelial cells, used as a model... -
Federal
Cellular responses to
U.S. Department of Health & Human Services —
Background Plasmodium falciparum erythrocyte membrane protein-1, a variant antigen of the malaria parasite, is potentially a target for the immune response. It would... -
Federal
The evaluation of yeast derivatives as adjuvant of the immune response to the Bm86 antigen in cattle: Correction
U.S. Department of Health & Human Services —
The evaluation of yeast derivatives as adjuvant of the immune response to the Bm86 antigen in cattle: Correction