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Federal
Cell-cell interactions in synovitis: Endothelial cells and immune cell migration
U.S. Department of Health & Human Services —
Leukocyte ingress into the synovium is a key process in the pathogenesis of rheumatoid arthritis and other inflammatory conditions. In this review, the role of... -
Federal
Low-volume jet injection for intradermal immunization in rabbits
U.S. Department of Health & Human Services —
Background This study tested a low-volume (20–30 μl/20–30 μg DNA) jet injection method for intradermal delivery of a DNA vaccine. Jet injection offers the advantages... -
Federal
Age-dependent changes in 24-hour rhythms of catecholamine content and turnover in hypothalamus, corpus striatum and pituitary gland of rats injected with Freund's adjuvant
U.S. Department of Health & Human Services —
Background Little information is available on the circadian sequela of an immune challenge in the brain of aged rats. To assess them, we studied 24-hour rhythms in... -
Federal
Enhanced immunogenicity of a functional enzyme by T cell epitope modification
U.S. Department of Health & Human Services —
Background T helper epitopes are necessary for the induction of high titers of antigen-specific IgG antibodies. We are interested in the epitope modification of... -
Federal
Report to Congress on Immunity from Prosecution for Mandated Reporters
U.S. Department of Health & Human Services —
This report to Congress provides an overview of information collected from professionals in the field affected by immunity issues related to the response and... -
Federal
Joint disease caused by defective gp130-mediated STAT signaling
U.S. Department of Health & Human Services —
IL-6 is a multifunctional cytokine produced by lymphoid and nonlymphoid cells; it regulates immune responses, acute-phase reactions, and inflammation. IL-6 signaling... -
Federal
Patent AT-E401392-T1: [Translated] SUBTYPE-MATCHED INACTIVATED WHOLE VIRUS VACCINE FOR THE TREATMENT OF PATIENTS WITH HIV INFECTION
U.S. Department of Health & Human Services —
Inactivated whole HIV of a particular subtype is used for vaccines and pharmaceutical compositions containing the vaccines. The vaccines can be used to treat... -
Federal
Cell-cell interactions in synovitis: Interactions between T cells and B cells in rheumatoid arthritis
U.S. Department of Health & Human Services —
In rheumatoid arthritis, T cells and B cells participate in the immune responses evolving in the synovial lesions. Interaction between T cells and B cells is probably... -
Federal
Expression of cytokine and chemokine mRNA and secretion of tumor necrosis factor-α by gallbladder epithelial cells: Response to bacterial lipopolysaccharides
U.S. Department of Health & Human Services —
Background In addition to immune cells, many other cell types are known to produce cytokines. Cultured normal mouse gallbladder epithelial cells, used as a model... -
Federal
Cellular responses to
U.S. Department of Health & Human Services —
Background Plasmodium falciparum erythrocyte membrane protein-1, a variant antigen of the malaria parasite, is potentially a target for the immune response. It would... -
Federal
The evaluation of yeast derivatives as adjuvant of the immune response to the Bm86 antigen in cattle: Correction
U.S. Department of Health & Human Services —
The evaluation of yeast derivatives as adjuvant of the immune response to the Bm86 antigen in cattle: Correction -
Federal
Patent AT-E401392-T1: [Translated] SUBTYPE-MATCHED INACTIVATED WHOLE VIRUS VACCINE FOR THE TREATMENT OF PATIENTS WITH HIV INFECTION
U.S. Department of Health & Human Services —
Inactivated whole HIV of a particular subtype is used for vaccines and pharmaceutical compositions containing the vaccines. The vaccines can be used to treat... -
Federal
Patent AT-E400189-T1: [Translated] DELIVERY OF DISEASE CONTROL AGENTS IN AQUACULTURE USING YEAST CONTAINING BIOACTIVE PROTEINS
U.S. Department of Health & Human Services —
This invention is directed to the use of fungal cells which are used as feed components in aquaculture or agriculture, and which also contain exogenous peptides,... -
Federal
Patent AT-E401404-T1: [Translated] LIGAND FOR RECEPTOR ACTIVATOR OF NF-KAPPA B, LIGAND IS A MEMBER OF THE TNF SUPERFAMILY
U.S. Department of Health & Human Services —
Isolated receptors, DNAs encoding such receptors, and pharmaceutical compositions made therefrom, are disclosed. The isolated receptors can be used to regulate an... -
Federal
Patent AT-E400278-T1: [Translated] IMMUNOMODULATING OLIGOSACCHARIDES
U.S. Department of Health & Human Services —
The present invention relates to a method for enhancing the immune system and the treatment and/or prevention of immune system related disorders in a mammal,... -
Federal
Patent AT-E400030-T1: [Translated] METHOD FOR IDENTIFYING T CELL PITOPES AND ITS APPLICATION TO PRODUCING MOLECULES WITH REDUCED IMMUNOGENICITY
U.S. Department of Health & Human Services —
This invention relates to a novel approach for identification of T-cell epitopes, that give rise to an immune reaction in a living host. By means of this novel method... -
Federal
Patent AT-E400293-T1: [Translated] SIGNAL-1/SIGNAL-2 BIFUNCTIONAL PEPTIDE INHIBITORS
U.S. Department of Health & Human Services —
A novel peptide sequence having the general formula AB wherein each of A and B represent a chain of amino acid residues and wherein said A chain is capable of binding... -
Federal
Patent AT-E401406-T1: [Translated] CHICKEN ANAEMIA VIRUS MUTANT, VACCINES, AND USES BASED ON VIRUS PROTEIN VP3, OR VIRUS SEQUENCES ENCODING THEREOF
U.S. Department of Health & Human Services —
Novel proteins of the Chicken Anemia Virus are described and compositions for preventing or treating infections with that virus (CAV), in particular vaccines less... -
Federal
Per- and polyfluoroalkyl substances along the St Louis River and in the Duluth, MN area 2019-2021
Department of the Interior —
Tree swallow nest boxes were deployed at sites proximal to two putative aqueous film forming foam (AFFF) sources in the Duluth, MN area, as well as along the St....