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Federal
Analysis of strain and regional variation in gene expression in mouse brain
U.S. Department of Health & Human Services —
Background We performed a statistical analysis of a previously published set of gene expression microarray data from six different brain regions in two mouse strains.... -
Federal
Vasopressin-dependent flank marking in golden hamsters is suppressed by drugs used in the treatment of obsessive-compulsive disorder
U.S. Department of Health & Human Services —
Background Alterations in arginine vasopressin regulation and secretion have been proposed as one possible biochemical abnormality in patients with obsessive-... -
Federal
Decreased insulin binding to mononuclear leucocytes and erythrocytes from dogs after S-Nitroso-N-Acetypenicillamine administration
U.S. Department of Health & Human Services —
Background Nitric oxide (NO) and oxygen free-radicals play an important part in the destruction of beta-cells in auto- immune diabetes although the precise mechanism... -
Federal
Abnormal expression of p27kip1 protein in levator ani muscle of aging women with pelvic floor disorders – a relationship to the cellular differentiation and degeneration
U.S. Department of Health & Human Services —
Background Pelvic floor disorders affect almost 50% of aging women. An important role in the pelvic floor support belongs to the levator ani muscle. The p27/kip1... -
Federal
The attributable mortality and length of intensive care unit stay of clinically important gastrointestinal bleeding in critically ill patients
U.S. Department of Health & Human Services —
Objective To estimate the mortality and length of stay in the intensive care unit (ICU) attributable to clinically important gastrointestinal bleeding in mechanically... -
Federal
A successful pregnancy following SEM fine tuning of hormonal priming
U.S. Department of Health & Human Services —
Background Manipulation of the uterine epithelium utilising standard dose exogenous oestrogen (E2) and progesterone (P4) has been shown to achieve a mature secretory... -
Federal
A new device for 100 per cent humidification of inspired air
U.S. Department of Health & Human Services —
A new humidifier for use during mechanical ventilation in endotracheally intubated patients is described and tested. The humidifier is based on a heat-moisture... -
Federal
Molecular distinction amongst varieties of Mulberry using RAPD and DAMD profiles
U.S. Department of Health & Human Services —
Background Mulberry trees are the most important host for rearing mulberry silkworms in sericulture. Improved varieties of mulberry tree have been developed through... -
Federal
Comparison of performance-based measures among native Japanese, Japanese-Americans in Hawaii and Caucasian women in the United States, ages 65 years and over: a cross-sectional study
U.S. Department of Health & Human Services —
Background Japanese (both in Japan and Hawaii) have a lower incidence of falls and of hip fracture than North American and European Caucasians, but the reasons for... -
Federal
Measuring access to effective care among elderly medicare enrollees in managed and fee-for-service care: a retrospective cohort study
U.S. Department of Health & Human Services —
Background Our aim was to compare access to effective care among elderly Medicare patients in a Staff Model and Group Model HMO and in Fee-for-Service (FFS) care.... -
Federal
Separate urinary bladder and prostate neurons in the central nervous system of the rat: simultaneous labeling with two immunohistochemically distinguishable pseudorabies viruses
U.S. Department of Health & Human Services —
Background This work examines the central nervous system distribution of virus-labeled neurons from the rat urinary bladder and the prostate simultaneously within the... -
Federal
Experience collecting interim data on mortality: an example from the RALES study
U.S. Department of Health & Human Services —
Introduction The Randomized Aldactone Evaluation Study (RALES) randomized 822 patients to receive 25 mg spironolactone daily and 841 to receive placebo. The primary... -
Federal
The molecular genetic linkage map of the model legume
U.S. Department of Health & Human Services —
Background The legume Medicago truncatula has emerged as a model plant for the molecular and genetic dissection of various plant processes involved in rhizobial,... -
Federal
Receptor protein tyrosine kinase EphB4 is up-regulated in colon cancer
U.S. Department of Health & Human Services —
Background We have used commercially available cDNA arrays to identify EphB4 as a gene that is up-regulated in colon cancer tissue when compared with matched normal... -
Federal
Do we need clinical trials to test the ability of transdermal HRT to prevent coronary heart disease?
U.S. Department of Health & Human Services —
Postmenopausal hormone replacement therapy (HRT) with oral oestrogen was predicted to reduce coronary heart disease (CHD) risk by 50%. Randomized controlled trials... -
Federal
A new way to rapidly create functional, fluorescent fusion proteins: random insertion of GFP with an
U.S. Department of Health & Human Services —
Background The jellyfish green fluorescent protein (GFP) can be inserted into the middle of another protein to produce a functional, fluorescent fusion protein.... -
Federal
Mutant loxP vectors for selectable marker recycle and conditional knock-outs
U.S. Department of Health & Human Services —
Background Gene disruption by targeted integration of transfected constructs becomes increasingly popular for studies of gene function. The chicken B cell line DT40... -
Federal
Computational discovery of sense-antisense transcription in the human and mouse genomes
U.S. Department of Health & Human Services —
Overlapping but oppositely oriented transcripts have the potential to form sense-antisense perfect double-stranded (ds) RNA duplexes. A bioinformatics approach has... -
Federal
Research Article: Journal of Biomedicine and Biotechnology
U.S. Department of Health & Human Services —
An intense suppression of T cell proliferation to mitogens and to antigens is observed in a large number of parasitic infections. The impairment of T cell... -
Federal
Epstein-Barr virus encoded nuclear protein EBNA-3 binds a novel human uridine kinase/uracil phosphoribosyltransferase
U.S. Department of Health & Human Services —
Background Epstein-Barr virus (EBV) infects resting B-lymphocytes and transforms them into immortal proliferating lymphoblastoid cell lines (LCLs) in vitro. The...