288 datasets found
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Federal
Combined space stressors induce independent behavioral deficits predicted by early peripheral blood monocytes (flow cytometry)
National Aeronautics and Space Administration —
Interplanetary space travel poses many hazards to the human body. To protect astronaut health and performance on critical missions, there is first a need to... -
Federal
Influence of Sex Hormones on Nervous System and Musculoskeletal Health in Micro and Martian Fractional Gravity in Rat Analogues (Force Plate; Soleus)
National Aeronautics and Space Administration —
Gonadal hormones, such as testosterone and estradiol, modulate muscle size and strength in males and females. However, the influence of sex hormones on muscle... -
Federal
Advancing the automation of plant nucleic acid extraction for rapid diagnosis of plant diseases in space
National Aeronautics and Space Administration —
Human space exploration missions will continue the development of sustainable plant cultivation in what are obviously novel habitat settings. Effective pathology... -
Federal
Gene Expression Profile Changes due to Bleomycin-Induced DNA Damage in Human Fibroblasts in Space
National Aeronautics and Space Administration —
To understand gene expression responses in confluent human fibroblast in microgravity conditions to bleomycin treatment. Confluent human fibroblasts AG01522 were... -
Federal
Characterization of mouse ocular response to a 35-day spaceflight mission: Evidence of blood-retinal barrier disruption and ocular adaptations - Proteomics data
National Aeronautics and Space Administration —
The health risks associated with spaceflight-induced ocular structural and functional damage has become a recent concern for NASA. The goal of the present study was... -
Federal
Transcriptional profiling of lungs from mice flown on the RR-23 mission
National Aeronautics and Space Administration —
The objective of the RR-23 mission was to better understand the effects of spaceflight on the eyes, specifically on the structure and function of the arteries, veins,... -
Federal
Osteocytes transcriptome is altered during spaceflight
National Aeronautics and Space Administration —
Bone loss is one of the major health problems for astronauts during long-term spaceflight and for patients during prolonged bed rest or paralysis. Growing evidence... -
Federal
Transcriptional profiling of thymus from mice flown on the RR-9 mission
National Aeronautics and Space Administration —
The objective of the Rodent Research-9 (RR-9) mission was to use mice to understand the molecular basis of phenomena that affect astronauts during long-duration... -
Federal
Plant Gravity Perception: Pilot (PGP Pilot)
National Aeronautics and Space Administration —
This study examined tissue-specific early transcriptional responses upon reorientation in wild type and starchless pgm-1 mutant seedlings of Arabidopsis. Seedlings... -
Federal
Transcriptional profiling, protein expression profiling, and phosphoprotein profiling of kidneys from mice flown on the RR-10 mission
National Aeronautics and Space Administration —
The objective of the Rodent Research-10 Mission (RR-10) was to investigate how spaceflight affects the cellular and molecular mechanisms of normal bone tissue... -
Federal
Draft Genome Sequences of Members of the family Methylobacteriaceae Associated with the International Space Station
National Aeronautics and Space Administration —
Draft Genome Sequences of isolates belonging to family Methylobacteriaceae Isolated from the International Space Station -
Federal
International Space Station - Microbial Observatory of Pathogenic Virus, Bacteria, and Fungi project
National Aeronautics and Space Administration —
This study investigated the interplay between the microbial community of the International Space Station and its crew. Environmental samples were collected from 8... -
Federal
Microbiome profiling of feces from mice flown on the RR-10 mission
National Aeronautics and Space Administration —
The objective of the Rodent Research-10 Mission (RR-10) was to investigate how spaceflight affects the cellular and molecular mechanisms of normal bone tissue... -
Federal
Plant Gravity Perception (PGP) Flight Study
National Aeronautics and Space Administration —
This study investigated plant responses to a range of gravity treatments. Altered gravity was achieved by growing seedlings on the ISS within the centrifuge of the... -
Federal
The Arabidopsis spaceflight transcriptome: a comparison of whole plants to discrete root, hypocotyl and shoot responses to the orbital environment
National Aeronautics and Space Administration —
Arabidopsis thaliana was evaluated for its response to the spaceflight environment in three replicated experiments on the International Space Station. Two approaches... -
Federal
Arabidopsis transcriptome in Virgin Galactic human-tended suborbital spaceflight
National Aeronautics and Space Administration —
The Virgin Galactic Unity 22 mission conducted the first astronaut-manipulated suborbital spaceflight experiment. The experiment examined the operationalization of... -
Federal
Characterization of Biofilm Formation, Growth, and Gene Expression on Different Materials and Environmental Conditions in Microgravity (Morphology of Pseudomonas aeruginosa biofilms)
National Aeronautics and Space Administration —
Microorganisms' natural ability to live as organized multicellular communities – also known as biofilms – provides them with unique survival advantages. For instance,... -
Federal
Drosophila parasitoids go to space: Unexpected effects of spaceflight on hosts and their parasitoids - Drosophila data
National Aeronautics and Space Administration —
In this study, fruit flies and their parasitic wasps were sent to the ISS to examine changes in host immunity and parasite virulence. Key findings from this work are... -
Federal
Spaceflight-Induced Gene Expression Profiles in the Mouse Brain Are Attenuated by Treatment with the Antioxidant BuOE - Cerebral Cortex
National Aeronautics and Space Administration —
The demands of deep space pose a health risk to the central nervous system that has long been a concern when sending humans to space. While little is known about how... -
Federal
Transcription profiling by array of the response of Arabidopsis cultivar Columbia etiolated seedlings and undifferentiated tissue culture cells to the spaceflight environment
National Aeronautics and Space Administration —
We address a key baseline question of whether gene expression changes are induced by the orbital environment, and then we ask whether undifferentiated cells, cells...
288 datasets found