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Federal
Low dose ionizing radiation treated lymphoblastoid cells recent views
National Aeronautics and Space Administration —
Irradiated cell lines exposed to 1-10 cGy 2 Lymphoblastoid cell lines (GM15510 and GM15036) irradiated 1 2.5 5 7.5 10 cGy RNA is isolated and labeled using a T7... -
Federal
Growth rate of mammary cancers arising in irradiated mice is associated with pattern of immune infiltrate recent views
National Aeronautics and Space Administration —
To determine how host irradiation affects tumor profiles in 10 month aged mice treated with HZE or gamma irradiation. -
Federal
RAD51 Interconnects Between DNA Replication DNA Repair and Immunity recent views
National Aeronautics and Space Administration —
RAD51 a multifunctional protein plays a central role in DNA replication and homologous recombination repair and is known to be involved in cancer development. We... -
Federal
DNA copy number analysis from mice with radiation-induced acute myeloid leukemia recent views
National Aeronautics and Space Administration —
Certain mouse strains such as CBA C3H and RFM have high incidence of radiation-induced acute myeloid leukemia (AML). The data in this series wer generated by using... -
Federal
IMR90 radiation bystander time-course experiment 0.5Gy alpha particle recent views
National Aeronautics and Space Administration —
The radiation bystander effect is an important component of the overall biological response of tissues and organisms to ionizing radiation. Little is known about the... -
Federal
Expression profiling of murine lung 70 days following exposure to fractionated or acute dose of 1.0 Gy 56Fe- particle irradiation recent views
National Aeronautics and Space Administration —
Irradiation of the K-rasLA1 mouse model with a fractionated dose of 1.0Gy 56Fe- particles increases the incidence of invasive carcinoma compared to unirradiated... -
Federal
Response of mammary tissue to high-LET HZE particle (Silicon ions) radiation or low-LET gamma-rays recent views
National Aeronautics and Space Administration —
Transcriptional profiling of mammary tissue irradiated at 10 weeks of age with either 100 cGy sparsely ionizing gamma-rays or 10 cGy or 30 cGy densely ionizing... -
Federal
Low dose (0.04 Gy) irradiation (LDR) and hindlimb unloading (HLU) microgravity in mice: retina transcriptomic and epigenomic data recent views
National Aeronautics and Space Administration —
The purpose of the present study was to evaluate damage in brain and eye in a ground-based model for spaceflight which includes prolonged unloading and low-dose... -
Federal
Transcription profiling of rat keratinocytes exposed to a 56Fe ion beam recent views
National Aeronautics and Space Administration —
The purpose of the present work was to examine gene expression patterns in a rat keratinocyte line exposed to a 56Fe ion beam Experiment Overall Design: The cells... -
Federal
Exposure to ionizing radiation induced persistent gene expression changes in mouse mammary gland recent views
National Aeronautics and Space Administration —
Six to eight week old female C57BL/6J mice were exposed to 2 Gy of whole body xce xb3 radiation and mammary glands were surgically removed 2-month after radiation.... -
Federal
Gene expression data from 4T1 irradiated tumors treated with TGFbeta blockade recent views
National Aeronautics and Space Administration —
Accumulating data support the concept that ionizing radiation therapy (RT) has the potential to convert the tumor into an in situ individualized vaccine; however this... -
Federal
Global DNA methylation profiling of radiation-induced rat mammary carcinomas recent views
National Aeronautics and Space Administration —
To investigate DNA methylation patterns in rat mammary carcinomas induced by ionizing radiation. DNA methylation patterns were analyzed in radiation-induced rat... -
Federal
Exposure to ionizing radiation induced persistent gene expression changes in mouse mammary gland recent views
National Aeronautics and Space Administration —
Six to eight week old female C57BL/6J mice were exposed to 2 Gy of whole body xce xb3 radiation and mammary glands were surgically removed 2-month after radiation.... -
Federal
Gene expression profiling of PBL in response to ionising radiation and modeled microgravity recent views
National Aeronautics and Space Administration —
BACKGROUND: Ionizing radiation (IR) can be extremely harmful for human cells since an improper DNA-damage response (DDR) to IR can contribute to carcinogenesis... -
Federal
Radiation responses in peripheral white blood cells of smokers and non-smokers recent views
National Aeronautics and Space Administration —
Understanding the possible impact of potential confounding factors is necessary for any approach to radiation biodosimetry. Potential confounding factors have not... -
Federal
Comparison of gene expression profiles of normal human bronchial epithelial cells in 2D and 3D cultural conditions recent views
National Aeronautics and Space Administration —
The experiment is part of a project to study DNA repair process after ionizing radiation in organotypic 3-dimentional human bronchial epithlial cell culture. Human... -
Federal
Gamma radiation and HZE treatment of seedlings in Arabidopsis recent views
National Aeronautics and Space Administration —
Plants exhibit a robust transcriptional response to gamma radiation which includes the induction of transcripts required for homologous recombination and the... -
Federal
miRNA signature detection and countermeasures against HZE radiation exposure for tissue degeneration-Plasma recent views
National Aeronautics and Space Administration —
Biological risks associated with space radiation and microgravity are major concerns for long-term space travel. Through a Systems Biology approach our previous NASA... -
Federal
Gene expression in human peripheral blood 48 hours after exposure to ionizing radiation recent views
National Aeronautics and Space Administration —
Analysis of human peripheral blood 48 hours after irradiation ex vivo with graded doses of gamma rays. Results have been used in building and testing classifiers to... -
Federal
Gene expression profiles of irradiated lung tissue in three mouse strains recent views
National Aeronautics and Space Administration —
The aim of our research is to clarify the mechanisms generating heterogeneity in response to C-ion irradiation that arise from individual genetic variations in...