-
Federal
Effect of varying amounts of simulated lunar soil batch #005 upon growth of lettuce explants
National Aeronautics and Space Administration —
The following general conclusions can be made concerning the use of tissue culture for assaying the effects of mineral elements from simulated lunar soil or other... -
Federal
Specific Host Metabolite and Gut Microbiome Alterations Are Associated with Bone-loss During Spaceflight
National Aeronautics and Space Administration —
Understanding the axis of the human microbiome and physiological homeostasis is an essential task in managing deep-space travel associated health risks. The NASA led... -
Federal
Root transcriptome remodeling of Arabidopsis in response to high levels of magnesium sulfate
National Aeronautics and Space Administration —
Martian regolith (unconsolidated surface material) is a potential medium for plant growth in bioregenerative life support systems during manned missions on Mars.... -
Federal
Dose-dependent skeletal deficits due to varied reductions in mechanical loading in rats (Femur - microCT, three-point bending, histomorphometry)
National Aeronautics and Space Administration —
Reduced skeletal loading leads to marked bone loss. Animal models of hindlimb suspension are widely used to assess alterations in skeleton during the course of... -
Federal
Dose-dependent skeletal deficits due to varied reductions in mechanical loading in rats (Tibia - pQCT)
National Aeronautics and Space Administration —
Reduced skeletal loading leads to marked bone loss. Animal models of hindlimb suspension are widely used to assess alterations in skeleton during the course of... -
Federal
Fifteen days of microgravity causes growth in calvaria of mice (STS-131)
National Aeronautics and Space Administration —
Bone growth may occur in spaceflight as a response to skeletal unloading and head-ward fluid shifts. While unloading causes significant loss of bone mass and density... -
Federal
Osteocytes transcriptome is altered during spaceflight
National Aeronautics and Space Administration —
Bone loss is one of the major health problems for astronauts during long-term spaceflight and for patients during prolonged bed rest or paralysis. Growing evidence... -
Federal
Spaceflight-induced (STS-62) vertebral bone loss in ovariectomized rats is associated with increased bone marrow adiposity and no change in bone formation
National Aeronautics and Space Administration —
There is often a reciprocal relationship between bone marrow adipocytes and osteoblasts, suggesting that marrow adipose tissue (MAT) antagonizes osteoblast... -
Federal
Toward countering muscle and bone loss with spaceflight: GSK3 as a potential target (Tibialis Anterior, RR9, Western Blot)
National Aeronautics and Space Administration —
We examined the effects of ~30 days of spaceflight on glycogen synthase kinase 3 (GSK3) content and inhibitory serine phosphorylation in murine muscle and bone...