288 datasets found
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Federal
Spatial characterization of microbial communities on multi-species leafy greens grown simultaneously in the Veggie vegetable production systems on the International Space Station VEG-03E
National Aeronautics and Space Administration —
Investigates the microbial communities of plants and Veggie pillow components with culturable and non-culturable methods providing qualitative and quantitative data.... -
Federal
Effects of Space Flight on Inflammasome Activation in the Brain of Mice (Cortex; ECLIA)
National Aeronautics and Space Administration —
Space exploration exposes astronauts to stressors that alter the immune response, rendering them vulnerable to infections and diseases. In this study, we aimed to... -
Federal
Effects of Spaceflight on Bone Microarchitecture in the Axial and Appendicular Skeleton in Growing Ovariectomized Rats from STS-62
National Aeronautics and Space Administration —
This study investigated the effects of a 14-day spaceflight on bone mass, density and microarchitecture in weight bearing (femur and humerus) and non-weight bearing... -
Federal
Characterization of Epigenetic Regulation in an Extraterrestrial Environment: The Arabidopsis Spaceflight Methylome
National Aeronautics and Space Administration —
When germinated and grown on-board the ISS (International Space Station), plant do not exhibit abnormal structures but they do have altered growth habits and this... -
Federal
Effects of Space Flight on Inflammasome Activation in the Brain of Mice (Hippocampus; ECLIA)
National Aeronautics and Space Administration —
Space exploration exposes astronauts to stressors that alter the immune response, rendering them vulnerable to infections and diseases. In this study, we aimed to... -
Federal
Effects of microgravity on human iPSC-derived neural organoids on the International Space Station - cortical organoids
National Aeronautics and Space Administration —
Research conducted on the International Space Station (ISS) in low-Earth orbit (LEO) has shown the effects of microgravity on multiple organs. To investigate the... -
Federal
Transcriptional analysis of lung from mice flown on the RR-6 mission
National Aeronautics and Space Administration —
The objective of the Rodent Research-6 (RR-6) study was to evaluate muscle atrophy in mice during spaceflight and to test the efficacy of a novel therapeutic to... -
Federal
Reproducible changes in gut microbiome reveal a shift in microbial and host metabolism during spaceflight
National Aeronautics and Space Administration —
Data were generated as part of a NASA-funded study (Turek F (PI) et al. Effects of Spaceflight on Gastrointestinal Microbiota in Mice: Mechanisms and Impact on Multi-... -
Federal
Effects of low-dose oxygen ions and protons on cardiac function and structure in male C57BL/6J mice (western blot, histology, and immunohistochemistry)
National Aeronautics and Space Administration —
Purpose: Astronauts traveling beyond low Earth orbit will be exposed to high linear energy transfer charged particles. Because there is concern about the adverse... -
Federal
Transcriptional profiling of gastrocnemius muscle from rats flown on the SLS-1 mission
National Aeronautics and Space Administration —
The Spacelab Life Sciences (SLS) program was a series of payloads that used the facilities of an entire Spacelab module to conduct a variety of life science... -
Federal
SpaceX Inspiration4 Oral, Nasal, and Skin Metagenomic and Metatranscriptomic Microbial Swabs
National Aeronautics and Space Administration —
The SpaceX Inspiration4 mission was a 3-day mission with four private astronauts to low Earth orbit that occurred in September 2021. The crew collected biospecimen... -
Federal
Transcriptional profiling of the right gastrocnemius muscle from mice flown on the RR-1 mission
National Aeronautics and Space Administration —
In the NASA Rodent Research-1 (RR-1) validation study, ten 16-week-old female C57BL/6J mice were flown to the ISS for 37 days before euthanasia and subsequent... -
Federal
Transcriptional profiling of spleens from mice flown on the RR-9 mission
National Aeronautics and Space Administration —
The objective of the Rodent Research-9 (RR-9) mission was to use mice to understand the molecular basis of phenomena that affect astronauts during long-duration... -
Federal
Spatial characterization of microbial communities on multi-species leafy greens grown simultaneously in the Veggie vegetable production systems on the International Space Station VEG-03F
National Aeronautics and Space Administration —
Investigates the microbial communities of plants and Veggie pillow components with culturable and non-culturable methods providing qualitative and quantitative data.... -
Federal
Altered rodent gait characteristics after ~35 days in orbit aboard the International Space Station
National Aeronautics and Space Administration —
The long-term adaptations to microgravity and other spaceflight challenges within the confines of a spacecraft, and readaptations to weight-bearing upon reaching a... -
Federal
Artificial gravity partially protects space-induced neurological deficits in Drosophila melanogaster (Immunohistochemistry)
National Aeronautics and Space Administration —
Spaceflight poses risks to the central nervous system (CNS), and understanding neurological responses is important for future missions. We report CNS changes in... -
Federal
Artificial gravity partially protects space-induced neurological deficits in Drosophila melanogaster
National Aeronautics and Space Administration —
Spaceflight poses risks to the central nervous system (CNS), and understanding neurological responses is important for future missions. We report CNS changes in... -
Federal
Single-molecule long-read methylation profiling reveals regional DNA methylation regulated by Elongator Complex Subunit 2 in Arabidopsis roots experiencing spaceflight
National Aeronautics and Space Administration —
The Advanced Plant Experiment-04 - Epigenetic Expression (APEX-04-EpEx) experiment onboard the International Space Station examined the spaceflight-altered cytosine... -
Federal
Dose-dependent skeletal deficits due to varied reductions in mechanical loading in rats (Femur - microCT, three-point bending, histomorphometry)
National Aeronautics and Space Administration —
Reduced skeletal loading leads to marked bone loss. Animal models of hindlimb suspension are widely used to assess alterations in skeleton during the course of... -
Federal
Effect of spaceflight on liver from mice flown on the ISS for 33 days: transcriptional analysis
National Aeronautics and Space Administration —
The objective of the Rodent Research-9 (RR-9) mission was to use mice to understand the molecular basis of phenomena that affect astronauts during long-duration...
288 datasets found