210 datasets found for "Physical Environments"
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Federal
Bulk RNA sequencing and spatially resolved transcriptional profiling of hippocampi from mice flown on the RR-10 mission
National Aeronautics and Space Administration —
The objective of the Rodent Research-10 mission (RR-10) was to investigate how spaceflight affects the cellular and molecular mechanisms of normal bone tissue... -
Federal
Rodent Research-1 (RR1) NASA Validation Flight: Mouse eye transcriptomic and epigenomic data
National Aeronautics and Space Administration —
NASA's Rodent Research (RR) project is playing a critical role in advancing biomedical research on the physiological effects of space environments. Due to the limited... -
Federal
Spaceflight-Induced Gene Expression Profiles in the Mouse Brain Are Attenuated by Treatment with the Antioxidant BuOE - Cornu Ammonis 1
National Aeronautics and Space Administration —
The demands of deep space pose a health risk to the central nervous system that has long been a concern when sending humans to space. While little is known about how... -
Federal
Spaceflight Analogue Culture Enhances the Host-Pathogen Interaction Between Salmonella and a 3-D Biomimetic Intestinal Co-Culture Model
National Aeronautics and Space Administration —
Physical forces associated with spaceflight and spaceflight analogue culture regulate a wide range of physiological responses by both bacterial and mammalian cells... -
Federal
Dissecting Low Atmospheric Pressure Stress: Transcriptome Responses to the Components of Hypobaria in Arabidopsis [Experiment 1]
National Aeronautics and Space Administration —
Controlled hypobaria presents biology with an environment that is never encountered in terrestrial ecology, yet the apparent components of hypobaria are stresses... -
Federal
During development, the Sku5 mutant roots engage different genes than wild type WS roots, either on the ground or in spaceflight.
National Aeronautics and Space Administration —
The wild type WS plants and the Sku5 mutant plants in the WS background were germinated on ISS or on the ground and the gene expression profiles in roots at 4 days or... -
Federal
Rodent Research-1 (RR1) NASA Validation Flight: Mouse soleus muscle transcriptomic and epigenomic data
National Aeronautics and Space Administration —
NASA's Rodent Research (RR) project is playing a critical role in advancing biomedical research on the physiological effects of space environments. Due to the limited... -
Federal
37-Day microgravity exposure in 16-Week female C57BL/6J mice during the NASA Rodent Research 1 mission is associated with bone loss specific to weight-bearing skeletal sites (femur and vertebrae, micro computed tomography)
National Aeronautics and Space Administration —
Exposure to weightlessness in microgravity and elevated space radiation are associated with rapid bone loss in mammals, but questions remain about their mechanisms of... -
Federal
Head-Down Tilt As a Model for Intracranial and Intraocular Pressures, and Retinal Changes during Spaceflight (Subcutaneous Tissue and Subdural Space, Body Temperature and Intracranial Pressure Biotelemetry)
National Aeronautics and Space Administration —
This ground-based program was intended to address the etiology of visual system structural and functional changes observed in astronauts during both inflight and... -
Federal
Head-Down Tilt As a Model for Intracranial and Intraocular Pressures, and Retinal Changes during Spaceflight (Optic Nerve, MRI)
National Aeronautics and Space Administration —
This ground-based program was intended to address the etiology of visual system structural and functional changes observed in astronauts during both inflight and... -
Federal
Draft Genome Sequence of Solibacillus kalamii, Isolated from an Air Filter Aboard the International Space Station
National Aeronautics and Space Administration —
Solibacillus kalamii was isolated from a HEPA filter in the International Space Station. This strain was of particular interest due to the unique environment in which... -
Federal
HSFA2 functions in the physiological adaptation of undifferentiated plant cells to spaceflight microgravity environment
National Aeronautics and Space Administration —
The Heat Shock Factor A2 (HsfA2), as a part of the HSF network, is essential to the plant's response to almost any environmental stress and to the cellular... -
Federal
Arg1 functions in the physiological adaptation of undifferentiated plant cells to spaceflight
National Aeronautics and Space Administration —
In this study transcriptome profiling was used to gain insight into the spaceflight adaptation role of Altered response to gravity-1 (Arg1), a gene known to affect... -
Federal
BRIC-23 GeneLab Process Verification Test: Bacillus subtilis transcriptomic, proteomic, and metabolomic data
National Aeronautics and Space Administration —
Microbes interact with humans in complex ways and understanding how they respond to the spaceflight environment is important to the success of future manned... -
Federal
Microgravity induces proteomics changes involved in endoplasmic reticulum stress and mitochondrial protection
National Aeronautics and Space Administration —
To reveal outcomes of microgravity on molecular processes within the cellular environment we have employed a mass-spectrometry based proteomics approach. Proteomics... -
Federal
Whole metagenome profiles of particulates collected from the International Space Station.
National Aeronautics and Space Administration —
The microbial composition of the International Space Station (ISS) environment is of critical interest due to potential impact of its constituents on human health and... -
Federal
Rodent Research-1 (RR1) NASA Validation Flight: Mouse quadriceps muscle transcriptomic, proteomic, and epigenomic data
National Aeronautics and Space Administration —
NASA's Rodent Research (RR) project is playing a critical role in advancing biomedical research on the physiological effects of space environments. Due to the limited... -
Federal
Transcriptional analysis of kidneys from mice flown on the RR-7 mission
National Aeronautics and Space Administration —
The objective of the Rodent Research-7 mission (RR-7) was to study the impact of the space environment on the gut microbiota of two strains of mice and how any... -
Federal
Quantifying Cancellous Bone Structural Changes in Microgravity: Axial Skeleton Results from the RR-1 Mission
National Aeronautics and Space Administration —
Objective of this study was to further validate bone degradation in microgravity as site-specific and preferential to weight bearing bone. An objective of this study... -
Federal
Genetic dissection of the Arabidopsis spaceflight transcriptome: Are some responses dispensable for the physiological adaptation of plants to spaceflight?
National Aeronautics and Space Administration —
Experimentation on the International Space Station has reached the stage where repeated and nuanced transcriptome studies are beginning to illuminate the structural...
210 datasets found for "Physical Environments"