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Federal
Genetic studies of the Roma (Gypsies): a review
U.S. Department of Health & Human Services —
Background Data provided by the social sciences as well as genetic research suggest that the 8-10 million Roma (Gypsies) who live in Europe today are best described... -
Federal
Genomic structure of the gene for mouse germ-cell nuclear factor (GCNF). II. Comparison with the genomic structure of the human
U.S. Department of Health & Human Services —
Background: Germ-cell nuclear factor (GCNF, NR6AI) is an orphan nuclear receptor. Its expression pattern suggests it functions during embryogenesis, in the placenta... -
Federal
Two C or not two C: recurrent disruption of Zn-ribbons, gene duplication, lineage-specific gene loss, and horizontal gene transfer in evolution of bacterial ribosomal proteins
U.S. Department of Health & Human Services —
Background Ribosomal proteins are encoded in all genomes of cellular life forms and are, generally, well conserved during evolution. In prokaryotes, the genes for... -
Federal
Severe community-acquired meningitis
U.S. Department of Health & Human Services —
Community-acquired meningitis is associated with high morbidity and mortality. The epidemiology of community-acquired meningitis has changed over the past 15 years... -
Federal
Debate: Should the elderly receive thrombolytic therapy or primary angioplasty?
U.S. Department of Health & Human Services —
Thrombolysis and primary angioplasty are both recommended reperfusion strategies for elderly patients presenting with myocardial infarction (MI). Primary angioplasty... -
Federal
Phylogenetic variation and polymorphism at the Toll-like receptor 4 locus (
U.S. Department of Health & Human Services —
Background: Differences in responses to bacterial surface lipopolysaccharides (LPSs) are apparent between and within mammalian species. It has been shown in mice that... -
Federal
Childhood infections and asthma: at the crossroads of the hygiene and Barker hypotheses
U.S. Department of Health & Human Services —
The hygiene hypothesis states that childhood asthma develops as a result of decreased exposure to infectious agents during infancy and early childhood. This results... -
Federal
New immunosuppressive drugs in heart transplantation
U.S. Department of Health & Human Services —
Only a few randomized clinical trials have been performed so far in heart transplant recipients, mainly because of the relatively small number of heart transplants... -
Federal
Regional Partnership Grants National Cross-Site Evaluation (RPG-4)
U.S. Department of Health & Human Services —
To address the far-reaching consequences of adult substance use disorders on families and children, Congress authorized competitive grants to support partnerships... -
Federal
Pro/con clinical debate: The use of a protected specimen brush in the diagnosis of ventilator associated pneumonia
U.S. Department of Health & Human Services —
Although mechanical ventilation is instituted as a life-saving technique, it may lead to complications that can negatively impact on patients' morbidity and/or... -
Federal
Identification of four families of yCCR4- and Mg
U.S. Department of Health & Human Services —
Background The yeast yCCR4 factor belongs to the CCR4-NOT transcriptional regulatory complex, in which it interacts, through its leucine-rich repeat (LRR) motif with... -
Federal
Regional Partnership Grants National Cross-Site Evaluation (RPG-5 and RPG-6)
U.S. Department of Health & Human Services —
To address the far-reaching consequences of adult substance use disorders on families and children, Congress authorized competitive grants to support partnerships... -
Federal
Compendium Child Welfare
U.S. Department of Health & Human Services —
Child Welfare Training Grant funds are authorized each fiscal year for grants to public or other non-profit institutions of higher learning for special projects to... -
Federal
Design and intermediate results of the Lower Extremity Arterial Disease Event Reduction (LEADER)* trial of bezafibrate in men with lower extremity arterial disease [ISRCTN41194621]
U.S. Department of Health & Human Services —
Background Raised levels of both triglycerides and fibrinogen, each of which are reduced by bezafibrate, may contribute to lower extremity arterial disease (LEAD).... -
Federal
Understanding gastrointestinal perfusion in critical care: so near, and yet so far
U.S. Department of Health & Human Services —
An association between abnormal gastrointestinal perfusion and critical illness has been suggested for a number of years. Much of the data to support this idea comes... -
Federal
Physicians' preference values for hepatitis C health states and antiviral therapy: A survey
U.S. Department of Health & Human Services —
Background Physicians' perspectives regarding hepatitis C shape their approach to patient management. We used utility analysis to evaluate physicians' perceptions of... -
Federal
Histometric data obtained by in vivo confocal laser scanning microscopy in patients with systemic sclerosis
U.S. Department of Health & Human Services —
Background It would be a benefit if time-saving, non-invasive methods could give hints for diagnosing systemic sclerosis. To investigate the skin of patients with... -
Federal
Purification and partial characterization of bacillocin 490, a novel bacteriocin produced by a thermophilic strain of
U.S. Department of Health & Human Services —
Background Applications of bacteriocins as food preservatives have been so far limited, principally because of their low antimicrobial activity in foods. Nisin is the... -
Federal
Rheumatoid arthritis viewed using a headache paradigm
U.S. Department of Health & Human Services —
Results and new hypotheses in animal models often stimulate development of new paradigms in how we view rheumatoid arthritis (RA). The complexity of RA does, however,... -
Federal
Design of the Intravenous Magnesium Efficacy in Acute Stroke (IMAGES) trial [ISRCTN19943732]
U.S. Department of Health & Human Services —
The Intravenous Magnesium Efficacy in Acute Stroke (IMAGES) trial is a multicentre,randomised, placebo-controlled trial of magnesium sulphate (MgSO4) funded by the UK...