10 datasets found
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Federal
Caged and resident fish, Newton Creek, Superior WI, 2017
U.S. Environmental Protection Agency —
In 2017 the Wisconsin DNR reported observation of a high incidence of fish with fin erosion in Newton Creek, which originates near the site of the Calumet (later... -
Federal
Systematically evaluating read-across prediction and performance using a local validity approach characterized by chemical structure and bioactivity information
U.S. Environmental Protection Agency —
Read-across is a popular data gap filling technique within category and analogue approaches for regulatory purposes. Acceptance of read-across remains an ongoing... -
Federal
Predict_Organ_Toxicity_ChemResTox_Data
U.S. Environmental Protection Agency —
We use a supervised machine learning strategy to systematically investigate the relative importance of study type, machine learning algorithm, and type of descriptor... -
Federal
Development and validation of CYP26A1 inhibition assay for high-throughput screening
U.S. Environmental Protection Agency —
Dataset for Sakamuru, S., Ma, D., Pierro, J. D., Baker, N. C., Kleinstreuer, N., Cali, J. J., Knudsen, T. B., & Xia, M. (2024). Development and validation of... -
Federal
The ToxCast pipeline: updates to curve-fitting approaches and database structure
U.S. Environmental Protection Agency —
Supplemental files to accompany the manuscript: Feshuk et al., "The ToxCast Pipeline: Updates to Curve-fitting Approaches and Database Structure", DOI... -
Federal
MS Datasets and Analyses for Shenandoah River FHM Metabolomics
U.S. Environmental Protection Agency —
MS Datasets and Analyses for Shenandoah River FHM Metabolomics -
Federal
Bioactivity of the ubiquitous tire preservative 6PPD and degradant, 6PPD-quinone in fish and mammalian-based assays
U.S. Environmental Protection Agency —
The data set contains data for the following assays performed using 6PPD-quinone and/or 6PPD. 1) Larval fathead minnow transcriptomics; 2) larval fathead minnow... -
Federal
Assessing bioactivity-exposure profiles of fruit and vegetable extracts in the BioMAP profiling system
U.S. Environmental Protection Agency —
The ToxCast program has generated in vitro screening data on over a thousand chemicals to assess potential disruption of important biological processes and assist in... -
Federal
Evans_2022_PFAS_in-vitro_manuscript_ScienceHub_2022-6-24
U.S. Environmental Protection Agency —
Dataset of medium throughput (96 well plate) in vitro nuclear receptor activation assays for peroxisome proliferator activated receptor alpha (PPARa), PPAR gamma... -
Federal
A Workflow for Identifying Metabolically Active Chemicals to Complement in vitro Toxicity Screening
U.S. Environmental Protection Agency —
This data includes metabolite predictions for in vitro inactive chemicals, predictions of those metabolite's estrogen receptor binding activity, in vitro and in...
10 datasets found