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Federal
Expression data from drosophila melanogaster recent views
National Aeronautics and Space Administration —
Space travel presents unlimited opportunities for exploration and discovery but requires a more complete understanding of the immunological consequences of long-term... -
Federal
Expression data from C. elegans recent views
National Aeronautics and Space Administration —
We used microarrays to investigate the effects of microgravity and space radiation on the genome-wide expression of the C. elegans. Three technical replicates of wild... -
Federal
RR-1 and RR-3 mouse liver transcriptomics with and without ERCC control RNA spike-ins recent views
National Aeronautics and Space Administration —
Proper interpretation of RNA sequencing data requires an understanding of assay sensitivity and sources of variability. To this end the External RNA Control... -
Federal
RNA-Seq transcriptome analysis of reactive oxygen species gene network in Mizuna plants grown in long-term space flight recent views
National Aeronautics and Space Administration —
Space environment is suspected to generate reactive oxygen species (ROS) and induce oxidative stress in plants however little is known about the gene expression of... -
Federal
The Arabidopsis spaceflight transcriptome: a comparison of whole plants to discrete root hypocotyl and shoot responses to the orbital environment recent views
National Aeronautics and Space Administration —
Arabidopsis thaliana was evaluated for its response to the spaceflight environment in three replicated experiments on the International Space Station. Two approaches... -
Federal
Low dose ionizing radiation treated lymphoblastoid cells recent views
National Aeronautics and Space Administration —
Irradiated cell lines exposed to 1-10 cGy 2 Lymphoblastoid cell lines (GM15510 and GM15036) irradiated 1 2.5 5 7.5 10 cGy RNA is isolated and labeled using a T7... -
Federal
Quantitative evaluation of bioaerosols in different particle size fractions collected on the International Space Station (ISS) recent views
National Aeronautics and Space Administration —
Exposure to bioaerosols can negatively impact human health. On the International Space Station (ISS) this exposure differs to that on Earth due to lack of... -
Federal
HSFA2 functions in the physiological adaptation of undifferentiated plant cells to spaceflight microgravity environment recent views
National Aeronautics and Space Administration —
The Heat Shock Factor A2 (HsfA2) as a part of the HSF network is essential to the plant s response to almost any environmental stress and to the cellular homeostatic... -
Federal
Transient gene expression profile changes of confluent human fibroblast cells in spaceflight recent views
National Aeronautics and Space Administration —
Microgravity or an altered gravity environment from the static 1g has been shown to influence global gene expression patterns and protein levels in cultured cells or... -
Federal
International Space Station flight project EXTREMOPHILES recent views
National Aeronautics and Space Administration —
The International Space Station (ISS) is a unique habitat for humans and microorganisms. Here, we report the results of the ISS experiment EXTREMOPHILES, including... -
Federal
Transcription profiling of Drosophila after exposure to microgravity in the International Space Station and in a microgravity simulator recent views
National Aeronautics and Space Administration —
Larvae-Pupae transition flies (Drosophila) were recovered and transport for 3 days at 12-14C to arrest development until the launch site then exposed to RT (18-20C)... -
Federal
Metagenomic analysis of feces from mice flown on the RR-9 mission recent views
National Aeronautics and Space Administration —
The objective of the Rodent Research-9 (RR-9) mission was to use mice to understand the molecular basis of phenomena that affect astronauts during long-duration... -
Federal
Growth rate of mammary cancers arising in irradiated mice is associated with pattern of immune infiltrate recent views
National Aeronautics and Space Administration —
To determine how host irradiation affects tumor profiles in 10 month aged mice treated with HZE or gamma irradiation. -
Federal
The influence of simulated microgravity on the proteome of Daphnia magna recent views
National Aeronautics and Space Administration —
Background/Objectives: The waterflea Daphnia is an interesting candidate for bioregenerative life support systems (BLSS). These animals are particularly promising... -
Federal
Effect of a 91 day long stay in weightlessness on the International Space Station on mouse skin physiology recent views
National Aeronautics and Space Administration —
Comparative gene expression in skin between mice maintained in microgravity (0g) and normogravity (1g) environment. Six male C57Bl/J10 mice were housed for 91 days in... -
Federal
Transcription profiling of rat response to changes in developmental stage - 3 types of tissue 3 gravity conditions 2 developmental conditions recent views
National Aeronautics and Space Administration —
Transcriptional crosstalk between mammary gland liver and adipose tissue Experiment Overall Design: Pregnant and Lactating rats exposed to 3 gravity conditions -
Federal
Biological Research in Canisters-16 (BRIC-16): Investigations of the plant cytoskeleton in microgravity with gene profiling and cytochemistry recent views
National Aeronautics and Space Administration —
These investigations studied the fundamentals of how plants perceive gravity and develop in microgravity. It informs how gene regulation is altered by spaceflight... -
Federal
Gene-expression profiling of Saccharomyces cerevisiae irradiated by high-LET radiations recent views
National Aeronautics and Space Administration —
Ionizing radiations are categorized by linear energy transfer (LET) into low-LET and high-LET. High-LET is considered to have a higher relative biological... -
Federal
Low dose (0.04 Gy) irradiation (LDR) and hindlimb unloading (HLU) microgravity in mice: retina transcriptomic and epigenomic data recent views
National Aeronautics and Space Administration —
The purpose of the present study was to evaluate damage in brain and eye in a ground-based model for spaceflight which includes prolonged unloading and low-dose... -
Federal
Transcription profiling of rat keratinocytes exposed to a 56Fe ion beam recent views
National Aeronautics and Space Administration —
The purpose of the present work was to examine gene expression patterns in a rat keratinocyte line exposed to a 56Fe ion beam Experiment Overall Design: The cells...