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Federal
Gamma radiation and HZE treatment of seedlings in Arabidopsis
National Aeronautics and Space Administration —
Plants exhibit a robust transcriptional response to gamma radiation which includes the induction of transcripts required for homologous recombination and the... -
Federal
Impact of spaceflight on gene expression in cultured human mesenchymal stem/stromal cell
National Aeronautics and Space Administration —
With technological advancements, human's desire to explore space is growing and more people are staying longer at the international space station (ISS). The impact of... -
Federal
Effects of microgravity on human iPSC-derived neural organoids on the International Space Station - cortical organoids
National Aeronautics and Space Administration —
Research conducted on the International Space Station (ISS) in low-Earth orbit (LEO) has shown the effects of microgravity on multiple organs. To investigate the... -
Federal
Spaceflight Modulates Gene Expression in Astronauts
National Aeronautics and Space Administration —
Astronauts are exposed to a unique combination of stressors during spaceflight, which leads to alterations in their physiology and potentially increases their... -
Federal
Plant Gravity Perception: Pilot (PGP Pilot)
National Aeronautics and Space Administration —
This study examined tissue-specific early transcriptional responses upon reorientation in wild type and starchless pgm-1 mutant seedlings of Arabidopsis. Seedlings... -
Federal
Bulk RNA sequencing and spatially resolved transcriptional profiling of cerebellums from mice flown on the RR-10 mission
National Aeronautics and Space Administration —
The objective of the Rodent Research-10 mission (RR-10) was to investigate how spaceflight affects the cellular and molecular mechanisms of normal bone tissue... -
Federal
Real-time quantitative PCR analysis of human cardiovascular progenitor cells flown aboard the International Space Station
National Aeronautics and Space Administration —
Adult and neonatal human cardiovacular progenitor cell clonal populations were flown aboard the ISS for 12 days prior to fixation in RNAprotect. Gene expression... -
Federal
Spatial characterization of microbial communities on multi-species leafy greens grown simultaneously in the Veggie vegetable production systems on the International Space Station VEG-03E
National Aeronautics and Space Administration —
Investigates the microbial communities of plants and Veggie pillow components with culturable and non-culturable methods providing qualitative and quantitative data.... -
Federal
Characterizing Epigenetic Changes in Methylation Mutants (elp2-5 and met1-7) in Response to Spaceflight. [RNA-Seq]
National Aeronautics and Space Administration —
Epigenetic changes in the DNA methylome are increasingly shown to play an integral role in regulating gene expression necessary for plants adaption to environmental... -
Federal
STS-135 Cerebellum Transcriptomics
National Aeronautics and Space Administration —
Mice were flown onboard STS-135 and returned to Earth for analysis. Cerebellums were collected within 3-4 hours of landing and snap frozen in liquid nitrogen. Samples... -
Federal
STS-135: Mouse Liver Transcriptomics using RNA-Seq
National Aeronautics and Space Administration —
Female C57BL/6CR mice were flown onboard STS-135 for 13 days and returned to Earth for analysis. Livers were collected within 3-4 hours of landing and snap frozen in... -
Federal
Transcriptional profiling of thymus from mice flown on the RR-9 mission
National Aeronautics and Space Administration —
The objective of the Rodent Research-9 (RR-9) mission was to use mice to understand the molecular basis of phenomena that affect astronauts during long-duration... -
Federal
Effect of spaceflight on liver from mice flown on the ISS for 33 days: transcriptional analysis
National Aeronautics and Space Administration —
The objective of the Rodent Research-9 (RR-9) mission was to use mice to understand the molecular basis of phenomena that affect astronauts during long-duration... -
Federal
Comparing RNA-Seq and microarray gene expression data in two zones of the Arabidopsis root apex relevant to spaceflight.
National Aeronautics and Space Administration —
Premise of the study: The root apex is an important region involved in environmental sensing, but comprises a very small part of the root. Obtaining root apex... -
Federal
Combined space stressors induce independent behavioral deficits predicted by early peripheral blood monocytes (Behavioral Assays)
National Aeronautics and Space Administration —
Interplanetary space travel poses many hazards to the human body. To protect astronaut health and performance on critical missions, there is first a need to... -
Federal
Transcriptional profiling of livers from mice flown on the RR-23 mission
National Aeronautics and Space Administration —
The objective of the RR-23 mission was to better understand the effects of spaceflight on the eyes, specifically on the structure and function of the arteries, veins,... -
Federal
Transcriptional profiling of colon from mice flown on the RR-10 mission
National Aeronautics and Space Administration —
The objective of the Rodent Research-10 mission (RR-10) was to investigate how spaceflight affects the cellular and molecular mechanisms of normal bone tissue... -
Federal
Transcriptional profiling of spleens from mice flown on the RR-9 mission
National Aeronautics and Space Administration —
The objective of the Rodent Research-9 (RR-9) mission was to use mice to understand the molecular basis of phenomena that affect astronauts during long-duration... -
Federal
Arabidopsis transcriptome in Virgin Galactic human-tended suborbital spaceflight
National Aeronautics and Space Administration —
The Virgin Galactic Unity 22 mission conducted the first astronaut-manipulated suborbital spaceflight experiment. The experiment examined the operationalization of... -
Federal
STS-135 Liver Transcriptomics
National Aeronautics and Space Administration —
Mice were flown onboard STS-135 and returned to Earth for analysis. Livers were collected within 3-4 hours of landing and snap frozen in liquid nitrogen. Samples were...