3 datasets found
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Federal
Macrophages exposed continuously to lipopolysaccharide and other agonists that act via toll-like receptors exhibit a sustained and additive activation state
U.S. Department of Health & Human Services —
Background Macrophages sense microorganisms through activation of members of the Toll-like receptor family, which initiate signals linked to transcription of many... -
Federal
Superantigen antagonist peptides
U.S. Department of Health & Human Services —
The production of superantigenic exotoxins by Gram positive bacteria underlies the pathology of toxic shock syndrome. Future treatment strategies for superantigen-... -
Federal
T-cell-mediated control of autoimmunity
U.S. Department of Health & Human Services —
Inflammatory responses provoked by pathogens are antigen-specific in their induction but are nonspecific in their effects. Consequently, they are potentially damaging...
3 datasets found