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Federal
Discontinuous and non-discontinuous subgenomic RNA transcription in a nidovirus
U.S. Department of Health & Human Services —
Arteri-, corona-, toro- and roniviruses are evolutionarily related positive-strand RNA viruses, united in the order Nidovirales. The best studied nidoviruses, the... -
Federal
How long should angiotensin-converting enzyme inhibitors be given to patients following myocardial infarction: implications of the HOPE trial
U.S. Department of Health & Human Services —
Long-term treatment with angiotensin-converting enzyme inhibitors reduces post-infarction morbidity and mortality in patients with left ventricular (LV) systolic... -
Federal
PKQuest: capillary permeability limitation and plasma protein binding – application to human inulin, dicloxacillin and ceftriaxone pharmacokinetics
U.S. Department of Health & Human Services —
Background It is generally assumed that the tissue exchange of antibiotics is flow limited (complete equilibration between the capillary and the tissue water). This... -
Federal
Health Service Research (HSR) PubMed Queries
U.S. Department of Health & Human Services —
Health Service Research (HSR) PubMed Queries contains preformulated specialized PubMed searches on healthcare quality and costs. -
Federal
Impaired wound healing in mice deficient in a matricellular protein SPARC (osteonectin, BM-40)
U.S. Department of Health & Human Services —
Background SPARC is a matricellular protein involved in cell-matrix interactions. From expression patterns at the wound site and in vitro studies, SPARC has been... -
Federal
Ecdysteroids and oocyte development in the black fly
U.S. Department of Health & Human Services —
Background Oocyte development was studied in the autogenous black fly, Simulium vittatum (Diptera, Nematocera), a vector of Onchocerca volvulus, the causative agent... -
Federal
HIPK2 overexpression leads to stabilization of p53 protein and increased p53 transcriptional activity by decreasing Mdm2 protein levels
U.S. Department of Health & Human Services —
Background HIPK2 (homeodomain-interacting protein kinase 2) has been identified as a nuclear serine/threonine kinase. A central function of HIPK2 is repressing... -
Federal
Chromosomal mapping, gene structure and characterization of the human and murine
U.S. Department of Health & Human Services —
Background Rab GTPases are regulators of intracellular membrane traffic. The Rab27 subfamily consists of Rab27a and Rab27b. Rab27a has been recently implicated in... -
Federal
Utility of the Mayo End-Stage Liver Disease (MELD) score in assessing prognosis of patients with alcoholic hepatitis
U.S. Department of Health & Human Services —
Background Alcoholic hepatitis is characterized by acute, or acute-on-chronic hepatic failure and associated with a high mortality. Specific therapies should be... -
Federal
Dynamic contrast-enhanced magnetic resonance imaging of the sarcopenic muscle
U.S. Department of Health & Human Services —
Background Studies about capillarity of the aged muscle provided conflicting results and no data are currently available about the magnetic resonance imaging (MRI) in... -
Federal
Can Australian general practitioners effectively screen for diabetic retinopathy? A pilot study
U.S. Department of Health & Human Services —
Background Diabetes has been identified as one of the national health priority areas in Australia. After 20 years of diabetes most patients can be expected to develop... -
Federal
Single-dose rofecoxib for acute postoperative pain in adults: a quantitative systematic review
U.S. Department of Health & Human Services —
Background Rofecoxib is a cyclo-oxygenase 2 selective inhibitor. This systematic review of rofecoxib in acute pain examined studies in adults of analgesic efficacy... -
Federal
2, 4-Diamino-6- hydroxy pyrimidine inhibits NSAIDs induced nitrosyl-complex EPR signals and ulcer in rat jejunum
U.S. Department of Health & Human Services —
Background It has been suggested that one aspect of non-steroidal anti-inflammatory drugs induced intestinal damage is due to either uncoupling of mitochondrial... -
Federal
Envelope structure of
U.S. Department of Health & Human Services —
Background Many bacteria swim by rotating helical flagellar filaments [1]. Waterbury et al. [15] discovered an exception, strains of the cyanobacterium Synechococcus... -
Federal
Right and left prefrontal transcranial magnetic stimulation at 1 Hz does not affect mood in healthy volunteers
U.S. Department of Health & Human Services —
Background Prefrontal repetitive transcranial magnetic stimulation (rTMS) has been used to induce side-specific mood changes in volunteers and patients. To clarify... -
Federal
Carbamazepine reduces memory induced activation of mesial temporal lobe structures: a pharmacological fMRI-study
U.S. Department of Health & Human Services —
Background and Purpose It is not known whether carbamazepine (CBZ; a drug widely used in neurology and psychiatry) influences the blood oxygenation level dependent... -
Federal
Cytokine-stimulated T cells induce macrophage IL-10 production dependent on phosphatidylinositol 3-kinase and p70S6K: implications for rheumatoid arthritis
U.S. Department of Health & Human Services —
IL-10 is an anti-inflammatory cytokine produced in the joint in rheumatoid arthritis by macrophages and infiltrating blood lymphocytes. Regulation of its expression... -
Federal
Interconversion of
U.S. Department of Health & Human Services —
Background Within the family of green fluorescent protein (GFP) homologs, one can mark two main groups, specifically, fluorescent proteins (FPs) and non-fluorescent... -
Federal
Citrullination: a small change for a protein with great consequences for rheumatoid arthritis
U.S. Department of Health & Human Services —
A new autoantibody activity, which is almost 100% specific for rheumatoid arthritis (RA), has been found. The essential part of the B-cell epitope is a modified form...