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Federal
Conservation of long-range synteny and microsynteny between the genomes of two distantly related nematodes
U.S. Department of Health & Human Services —
To assess whether the pattern of high rates of genome rearrangement, with a bias towards within-chromosome events is true of nematodes in general, genome sequence was... -
Federal
Serum folate levels after UVA exposure: a two-group parallel randomised controlled trial
U.S. Department of Health & Human Services —
Background Photodegradation of certain vitamins such as riboflavins, carotinoids, tocopherol, and folate has been well-documented. Previous observations suggest that... -
Federal
Respiratory syncytial virus and TNFalpha induction of chemokine gene expression involves differential activation of Rel A and NF-kappaB1
U.S. Department of Health & Human Services —
Background Respiratory syncytial virus (RSV) infection of airway epithelial cells stimulates the expression and secretion of a variety of cytokines including the... -
Federal
Compound 527359: 18,22,26-Trimethyl-hentriacontyl cyanide
U.S. Department of Health & Human Services —
Chemical compound data from PubChem database. IUPAC Name: 19,23,27-trimethyldotriacontanenitrile. Molecular Formula: C35H69N. Molecular Weight: 503.9. This dataset... -
Federal
Percutaneous tracheostomy: comparison of Ciaglia and Griggs techniques
U.S. Department of Health & Human Services —
Background: Although the standard tracheostomy described in 1909 by Jackson has been extensively used in critical patients, a more simple procedure that can be... -
Federal
Research Article: Journal of Biomedicine and Biotechnology
U.S. Department of Health & Human Services —
Tamoxifen, a potent anticancer agent known to interrupt the enhanced estrogen activity of malignant mammary gland cells, was recently approved by the Food and Drug... -
Federal
Viruses, dendritic cells and the lung
U.S. Department of Health & Human Services —
The interaction between viruses and dendritic cells (DCs) is varied and complex. DCs are key elements in the development of a host response to pathogens such as... -
Federal
Tetraethylammonium block of water flux in Aquaporin-1 channels expressed in kidney thin limbs of Henle's loop and a kidney-derived cell line.
U.S. Department of Health & Human Services —
Background Aquaporin-1 (AQP1) channels are constitutively active water channels that allow rapid transmembrane osmotic water flux, and also serve as cyclic-GMP-gated... -
Federal
Characterization of subcellular localization and stability of a splice variant of G alpha
U.S. Department of Health & Human Services —
Background Alternative mRNA splicing of αi2, a heterotrimeric G protein α subunit, has been shown to produce an additional protein, termed sαi2. In the sαi2 splice... -
Federal
Functional associations of proteins in entire genomes by means of exhaustive detection of gene fusions
U.S. Department of Health & Human Services —
Background It has recently been shown that the detection of gene fusion events across genomes can be used for predicting functional associations of proteins,... -
Federal
A role of proton transfer in peroxidase-catalyzed process elucidated by substrates docking calculations
U.S. Department of Health & Human Services —
Background Previous kinetic investigations of fungal-peroxidase catalyzed oxidation of N-aryl hydroxamic acids (AHAs) and N-aryl-N-hydroxy urethanes (AHUs) revealed... -
Federal
Low-volume jet injection for intradermal immunization in rabbits
U.S. Department of Health & Human Services —
Background This study tested a low-volume (20–30 μl/20–30 μg DNA) jet injection method for intradermal delivery of a DNA vaccine. Jet injection offers the advantages... -
Federal
Induction of apoptosis in rat peripheral blood lymphocytes by the anticancer drug CI-994 (acetyldinaline)
U.S. Department of Health & Human Services —
Abstract CI-994 (acetyldinaline) is an investigational anticancer drug currently in clinical trials. In preclinical safety studies in rats and dogs, CI-994 resulted... -
Federal
Validation and results of a questionnaire for functional bowel disease in out-patients
U.S. Department of Health & Human Services —
Background The aim was to evaluate and validate a bowel disease questionnaire in patients attending an out-patient gastroenterology clinic in Greece. Methods This was... -
Federal
Simultaneous identification of
U.S. Department of Health & Human Services —
Background The glutathione S-transferase (GST) enzyme GSTP1 utilizes byproducts of oxidative stress. We previously showed that alleles of GSTP1 that encode the... -
Federal
The GOLD domain, a novel protein module involved in Golgi function and secretion
U.S. Department of Health & Human Services —
Background Members of the p24 (p24/gp25L/emp24/Erp) family of proteins have been shown to be critical components of the coated vesicles that are involved in the... -
Federal
Locations of several novel 2'-
U.S. Department of Health & Human Services —
Background Ribose 2'-O-methylation, the most common nucleotide modification in mammalian rRNA, is directed by the C/D box small nucleolar RNAs (snoRNAs). Thus far,... -
Federal
Compound 527240: Vetiselinenol
U.S. Department of Health & Human Services —
Chemical compound data from PubChem database. IUPAC Name: 2-(4a-methyl-8-methylidene-1,4,5,6,7,8a-hexahydronaphthalen-2-yl)propan-1-ol. Molecular Formula: C15H24O.... -
Federal
Debate: Are surrogate end-point studies worth the effort?
U.S. Department of Health & Human Services —
Surrogate end-points of cardiovascular disease can provide useful information in cross-sectional, prospective and interventional studies. They provide information on... -
Federal
Differential response to right unilateral ECT in depressed patients: impact of comorbidity and severity of illness [ISRCTN39974945]
U.S. Department of Health & Human Services —
Background Recent electroconvulsive therapy (ECT) efficacy studies of right unilateral (RUL) ECT may not apply to real life clinics with a wide range of patients with...