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2021-2022 NSDUH: Guide to Comparison of Population Percentages Across Geographies

Published by Substance Abuse and Mental Health Services Administration | U.S. Department of Health & Human Services | Catalog Last Checked: July 31, 2026 at 09:06 PM | Dataset Last Updated: September 06, 2025
Learn how to access and use p-value tables to compare state-level estimates from the 2021-2022 National Surveys on Drug Use and Health (NSDUH). Thep-value tablesaccompany the2021-2022 NSDUH State Estimates of Substance Use and Mental Disorderswhich contain 35 measures of substance use and mental health across the nation, four Census regions, 50 states, and the District of Columbia. The guide describes the files and how to use the p-value tables to determine whether differences between two geographic areas are statistically significant.

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