Search datasets
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Background In sporadic ovarian cancer, we have previously reported allele loss at D6S193 (62%) on chromosome 6q27, which suggested the presence of a putative tumour suppressor gene....
Search relevance: 167.76 | Views last month: 1 | Catalog Last Checked: September 10, 2026 at 07:48 PM -
Background Cystinosis is an autosomal recessive disorder characterised by an intralysosomal accumulation of cystine, and affected individuals progress to end-stage renal failure before...
Search relevance: 63.61 | Views last month: 0 | Catalog Last Checked: September 10, 2026 at 08:29 PM -
Background The proteinase-activated receptor 4 (PAR4) is a G-protein-coupled receptor activated by proteases such as thrombin and trypsin. Although activation of PAR4 has been shown to...
Search relevance: 54.84 | Views last month: 0 | Catalog Last Checked: September 10, 2026 at 07:55 PM -
The autoantigenic polymyositis/scleroderma (PM/Scl) complex was recently shown to be the human homologue of the yeast exosome, which is an RNA-processing complex. Our aim was to assess whether, in...
Search relevance: 50.55 | Views last month: 2 | Catalog Last Checked: September 10, 2026 at 08:23 PM -
Background The centromere is a specialized locus that mediates chromosome movement during mitosis and meiosis. This chromosomal domain comprises a uniquely packaged form of...
Search relevance: 46.40 | Views last month: 1 | Catalog Last Checked: September 10, 2026 at 08:00 PM -
Background Mucolipidosis type IV (MLIV) is an autosomal recessive lysosomal storage disorder characterized by severe neurologic and ophthalmologic abnormalities. Recently the MLIV gene,...
Search relevance: 45.03 | Views last month: 1 | Catalog Last Checked: September 10, 2026 at 07:51 PM -
Background Nocturnin was originally identified by differential display as a circadian clock regulated gene with high expression at night in photoreceptors of the African clawed frog,...
Search relevance: 44.87 | Views last month: 2 | Catalog Last Checked: September 10, 2026 at 07:50 PM -
Background The COP9/signalosome (CSN), a multiprotein complex consisting of eight subunits, is implicated in a wide variety of regulatory processes including cell cycle control, signal...
Search relevance: 40.68 | Views last month: 0 | Catalog Last Checked: September 10, 2026 at 08:15 PM
