Search datasets
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Background Oxidative stress, resulting in a marked increase in the level of oxygen free radicals (OFR), has been implicated in the etiology of diabetic neuropathy (DN). Antioxidant...
Search relevance: 125.80 | Views last month: 1 | Catalog Last Checked: September 10, 2026 at 07:35 PM -
The study of genetic polymorphisms has touched every aspect of pulmonary and critical care medicine. We review recent progress made using genetic polymorphisms to define pathophysiology, to...
Search relevance: 117.37 | Views last month: 0 | Catalog Last Checked: September 10, 2026 at 07:40 PM -
Background Circulating levels of tumor necrosis factor (TNF) and lymphotoxin-α (LT-α) have been associated with outcome in solid and hematologic malignancies. Within the TNF gene and the...
Search relevance: 110.05 | Views last month: 0 | Catalog Last Checked: September 10, 2026 at 07:52 PM -
Asthma is the most common chronic childhood disease in the developed nations, and is a complex disease that has high social and economic costs. Studies of the genetic etiology of asthma offer a...
Search relevance: 98.64 | Views last month: 3 | Catalog Last Checked: September 10, 2026 at 07:46 PM -
Genes in the human leukocyte antigen (HLA) region remain the most powerful disease risk genes in rheumatoid arthritis (RA). Several allelic variants of HLA-DRB1 genes have been associated with RA,...
Search relevance: 94.54 | Views last month: 2 | Catalog Last Checked: September 10, 2026 at 08:01 PM -
The fathead minnow (Pimephales promelas) is a key model of vertebrate toxicity. Standardized tests of toxicity in fathead minnow have been developed to support regulatory science, and much is...
Search relevance: 90.91 | Views last month: 2 | Catalog Last Checked: September 10, 2026 at 08:25 PM -
Background Breast cancer is hormone related, as are cancers of the endometrium, ovary, and prostate. Several studies have suggested that higher extracellular levels of androgens are...
Search relevance: 82.81 | Views last month: 1 | Catalog Last Checked: September 10, 2026 at 08:33 PM -
Background Single nucleotide polymorphisms (SNPs) are the foundation of powerful complex trait and pharmacogenomic analyses. The availability of large SNP databases, however, has...
Search relevance: 82.31 | Views last month: 2 | Catalog Last Checked: September 10, 2026 at 08:04 PM -
This study generated genetic polymorphism data at a genome scale by whole-genome shotgun DNA sequencing of Mariana Crow (Corvus Kubaryi). DNA was extracted from blood tissue originally collected...
Search relevance: 69.00 | Views last month: 1 | Catalog Last Checked: September 10, 2026 at 09:52 PM -
Pulmonary surfactant is a complex mixture of phospholipids and proteins, which is present in the alveolar lining fluid and is essential for normal lung function. Alterations in surfactant...
Search relevance: 67.35 | Views last month: 2 | Catalog Last Checked: September 10, 2026 at 08:12 PM -
Background Current efforts to study the genetic underpinnings of higher brain functions have been lacking appropriate phenotypes to describe cognition. One of the problems is that many...
Search relevance: 65.28 | Views last month: 1 | Catalog Last Checked: September 10, 2026 at 07:40 PM -
Background The association between the human cytotoxic T lymphocyte-associated antigen-4 (CTLA4) gene and insulin-dependent diabetes mellitus (IDDM) is unclear in populations. We...
Search relevance: 53.37 | Views last month: 1 | Catalog Last Checked: September 10, 2026 at 08:13 PM -
This data set contains a description of 3 mitochondrial DNA and 93 nuclear DNA Single Nucleotide Polymorphism (SNP) loci and sequence information developed through double digest restriction-site...
Search relevance: 45.33 | Views last month: 5 | Catalog Last Checked: September 10, 2026 at 08:26 PM -
Background Desmuslin is an α-dystrobrevin-interacting protein expressed primarily in heart and skeletal muscle. The desmuslin protein interacts with and is closely related to desmin, a...
Search relevance: 41.77 | Views last month: 2 | Catalog Last Checked: September 10, 2026 at 08:04 PM -
Asthma and associated phenotypes are complex traits most probably caused by an interaction of multiple disease susceptibility genes and environmental factors. Major achievements have occurred in...
Search relevance: 41.05 | Views last month: 3 | Catalog Last Checked: September 10, 2026 at 07:47 PM -
In sarcoidosis, host genetic factors are discussed as contributing to disease susceptibility and course. Since tumor necrosis factor (TNF)-α is a central mediator of granuloma formation and since...
Search relevance: 40.94 | Views last month: 0 | Catalog Last Checked: September 10, 2026 at 08:28 PM -
dbSNP is a database of single nucleotide polymorphisms (SNPs) and multiple small-scale variations that include insertions/deletions, microsatellites, and non-polymorphic variants.
Search relevance: 40.59 | Views last month: 4 | Catalog Last Checked: September 10, 2026 at 08:17 PM -
Background Women may be at increased risk for venous thromboembolism (VTE) as compared with men. We studied the effects of genetic and biochemical markers of thrombophilia in women, in...
Search relevance: 38.72 | Views last month: 3 | Catalog Last Checked: September 10, 2026 at 07:49 PM -
Background The Apo-1/Fas (CD95) molecule is an apoptosis-signaling cell surface receptor belonging to the tumor necrosis factor (TNF) receptor family. Both Fas and Fas ligand (FasL) are...
Search relevance: 38.55 | Views last month: 1 | Catalog Last Checked: September 10, 2026 at 08:29 PM -
The DICE (Database of Immune Cell Expression, Expression quantitative trait loci (eQTLs) and Epigenomics) project aims to understand the role of common genetic variations in human disease by (i)...
Search relevance: 37.98 | Views last month: 0 | Catalog Last Checked: October 24, 2026 at 12:04 AM
