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#1 Federal

Critical advances in septicemia and septic shock

Organization: U.S. Department of Health & Human Services
Dataset Last Updated: September 06, 2025

Recent advances suggest that toll-like receptors, various cytokines, cicosanoids, free radicals and macrophage migration inhibitory factor (MIF) play an important role in the pathobiology of...

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Search relevance: 1.00 | Views last month: 3 | Catalog Last Checked: September 07, 2025 at 01:58 PM

#2 Federal

Toll-like receptors: the key to the stable door?

Organization: U.S. Department of Health & Human Services
Dataset Last Updated: September 06, 2025

Severe sepsis continues to lead to critical illness. Few therapeutic options exist other than antibiotic therapy and general supportive care. Large numbers of patients continue to die as a...

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Search relevance: 1.00 | Views last month: 1 | Catalog Last Checked: September 07, 2025 at 04:51 PM

#3 Federal

Macrophages exposed continuously to lipopolysaccharide and other agonists that act via toll-like receptors exhibit a sustained and additive activation state

Organization: U.S. Department of Health & Human Services
Dataset Last Updated: September 06, 2025

Background Macrophages sense microorganisms through activation of members of the Toll-like receptor family, which initiate signals linked to transcription of many inflammation associated...

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Search relevance: 1.00 | Views last month: 0 | Catalog Last Checked: September 07, 2025 at 01:38 PM

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Critical advances in septicemia and septic shock

Toll-like receptors: the key to the stable door?

Macrophages exposed continuously to lipopolysaccharide and other agonists that act via toll-like receptors exhibit a sustained and additive activation state