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#1 Federal
T cells that are naturally tolerant to cartilage-derived type II collagen are involved in the development of collagen-induced arthritis
- Organization: U.S. Department of Health & Human Services
- Dataset Last Updated: September 06, 2025
The immunodominant T-cell epitope that is involved in collagen-induced arthritis (CIA) is the glycosylated type II collagen (CII) peptide 256-270. In CII transgenic mice, which express the...
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Search relevance: 1.00 | Views last month: 3 | Catalog Last Checked: July 31, 2026 at 09:27 PM
#2 Federal
The role of X-chromosome inactivation in female predisposition to autoimmunity
- Organization: U.S. Department of Health & Human Services
- Dataset Last Updated: September 06, 2025
We propose that the phenomenon of X-chromosome inactivation in females may constitute a risk factor for loss of T-cell tolerance; specifically that skewed X-chromosome inactivation in the thymus...
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Search relevance: 1.00 | Views last month: 2 | Catalog Last Checked: July 31, 2026 at 09:53 PM

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