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Background Many randomized trials involve measuring a continuous outcome - such as pain, body weight or blood pressure - at baseline and after treatment. In this paper, I compare four...
Search relevance: 1.00 | Views last month: 10 | Catalog Last Checked: September 10, 2026 at 08:17 PM -
Background It has been recognized that replicates of arrays (or spots) may be necessary for reliably detecting differentially expressed genes in microarray experiments. However, the...
Search relevance: 1.00 | Views last month: 5 | Catalog Last Checked: September 10, 2026 at 08:01 PM -
Analysis of subgroup results in a clinical trial is surprisingly unreliable, even in a large trial. This is the result of a combination of reduced statistical power, increased variance and the...
Search relevance: 1.00 | Views last month: 2 | Catalog Last Checked: September 10, 2026 at 08:33 PM -
Background Physicians reading the medical literature attempt to determine whether research studies are valid. However, articles with negative results may not provide sufficient...
Search relevance: 1.00 | Views last month: 2 | Catalog Last Checked: September 10, 2026 at 07:41 PM
