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#1 Federal
Loss of cellular adhesion to matrix induces p53-independent expression of PTEN tumor suppressor
- Organization: U.S. Department of Health & Human Services
- Dataset Last Updated: September 06, 2025
Background The tumor suppressor gene PTEN has been found mutated in many types of advanced tumors. When introduced into tumor cells that lack the wild-type allele of the gene, exogenous...
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Search relevance: 1.00 | Views last month: 1 | Catalog Last Checked: July 31, 2026 at 09:45 PM
#2 Federal
Activation of synovial fibroblasts in rheumatoid arthritis: lack of expression of the tumour suppressor PTEN at sites of invasive growth and destruction
- Organization: U.S. Department of Health & Human Services
- Dataset Last Updated: September 06, 2025
In the present study, we searched for mutant PTEN transcripts in aggressive rheumatoid arthritis synovial fibroblasts (RA-SF) and studied the expression of PTEN in RA. By automated...
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Search relevance: 1.00 | Views last month: 0 | Catalog Last Checked: July 31, 2026 at 09:19 PM

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