Found 58 datasets matching filters.
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The general objective of the study was to determine modulation of gene expression by environmental factors specifically simulation of microgravity with a special emphasis on bone formation. For...
Search relevance: 1.00 | Views last month: 1 | Published on: 2026-01-17 -
The effect of microgravity on gene expression in C.elegans was comprehensively analysed by DNA microarray (Agilent). Overall design: Mix staged C. elegans N2 was exposed microgravity for 10 days.
Search relevance: 1.00 | Views last month: 1 | Published on: 2025-08-04 -
Genome-wide detection of novel non-coding RNAs in S. cerevisiae by modulating an RNase P pathway through the depletion of a component RPP1. Nearly 400,000 36-mer oligonucleotide probes tiling the...
Search relevance: 1.00 | Views last month: 1 | Published on: 2026-04-13 -
BACKGROUND: Ionizing radiation (IR) can be extremely harmful for human cells since an improper DNA-damage response (DDR) to IR can contribute to carcinogenesis initiation. Perturbations in DDR...
Search relevance: 1.00 | Views last month: 1 | Published on: 2025-09-08 -
Cell cycle and cell proliferation are decoupled under altered gravity conditions. We have previously shown that semisolid cell cultures of Arabidopsis suffer overall genome changes in response to...
Search relevance: 1.00 | Views last month: 1 | Published on: 2026-04-13 -
We investigated differentially regulated and stably expressed genes in human Jurkat T lymphocytic cells in 5min simulated microgravity and hypergravity and compared expression profiles to identify...
Search relevance: 1.00 | Views last month: 1 | Published on: 2025-08-04 -
The present study concerns the effects of 21 days of sustained recumbence (bedrest) on skeletal muscle gene expression. 14 male subjects participated in normoxic bedrest (NBR) with muscle...
Search relevance: 1.00 | Views last month: 1 | Published on: 2025-08-04 -
In recent times long-term stay has become a common occurrence in the International Space Station (ISS). However adaptation to the space environment can sometimes pose physiological problems to the...
Search relevance: 1.00 | Views last month: 1 | Published on: 2025-10-20 -
BACKGROUND: Ionizing radiation (IR) can be extremely harmful for human cells since an improper DNA-damage response (DDR) to IR can contribute to carcinogenesis initiation. Perturbations in DDR...
Search relevance: 1.00 | Views last month: 0 | Published on: 2025-08-04 -
We investigated differentially regulated genes in human Jurkat T lymphocytic cells in 20s and 5min microgravity and in hypergravity and compared expression profiles to identify potential...
Search relevance: 1.00 | Views last month: 0 | Published on: 2026-01-03 -
Space radiations and microgravity both could cause DNA damage in cells but the effects of microgravity on DNA damage response to space radiations are still controversial. A mRNA microarray and...
Search relevance: 1.00 | Views last month: 0 | Published on: 2025-08-04 -
In recent times long-term stay has become a common occurrence in the International Space Station (ISS). However adaptation to the space environment can sometimes pose physiological problems to the...
Search relevance: 1.00 | Views last month: 0 | Published on: 2025-08-04 -
Space radiations and microgravity both could cause DNA damage in cells but the effects of microgravity on DNA damage response to space radiations are still controversial. A mRNA microarray and...
Search relevance: 1.00 | Views last month: 0 | Published on: 2025-08-04 -
Gene expression changes induced by acute skeletal muscle unloading which leads to physiological changes including muscle atrophy fibre-type switching and loss of ability to transition between...
Search relevance: 1.00 | Views last month: 0 | Published on: 2025-08-04 -
Ionizing radiations are categorized by linear energy transfer (LET) into low-LET and high-LET. High-LET is considered to have a higher relative biological effectiveness (RBE) than low-LET...
Search relevance: 1.00 | Views last month: 0 | Published on: 2025-08-04 -
Microarray Analysis of Space-flown Murine Thymus Tissue Reveals Changes in Gene Expression Regulating Stress and Glucocorticoid Receptors. We used microarrays to detail the gene expression of...
Search relevance: 1.00 | Views last month: 0 | Published on: 2025-08-04 -
We investigated differentially regulated genes in human myelomonocytic U937 cells in 20s and 5min microgravity and in hypergravity and compared expression profiles to identify potential...
Search relevance: 1.00 | Views last month: 0 | Published on: 2025-09-08 -
Accumulating data suggest that the biological responses to high and low doses of radiation are qualitatively different necessitating the direct study of low dose responses. Most such studies have...
Search relevance: 1.00 | Views last month: 0 | Published on: 2025-08-04 -
We investigated differentially regulated genes in human Jurkat T lymphocytic cells in 20s and 5min microgravity and in hypergravity and compared expression profiles to identify potential...
Search relevance: 1.00 | Views last month: 0 | Published on: 2025-08-04 -
We report the findings of an animal experiment onboard STS-135 investigating the molecular aspects of the impact of spaceflight on retinal biology by performing differential gene expression...
Search relevance: 1.00 | Views last month: 0 | Published on: 2026-04-13
