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Background Somatic cell mutants can be informative in the analysis of a wide variety of cellular processes. The use of map-based positional cloning strategies in somatic cell hybrids to...
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DNA microarrays were used to examine the temporal program of gene expression following treatment of a human prostate cancer cell line with androgen. Significant changes in levels of transcripts of...
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A robust semi-parametric normalization technique has been developed, based on the assumption that the large majority of genes will not have their relative expression levels changed from one...
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A simple and robust non-linear method is presented for normalization using array signal distribution analysis and cubic splines. Both the regression and spline-based methods described performed...
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A combination of linear RNA amplification and DNA microarray hybridization has allowed the determination of expression profiles of individual imaginal discs and larval tissues and the...
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