Search datasets
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The Chemical and Product Categories database (CPCat) catalogs the use of over 40,000 chemicals and their presence in different consumer products. The chemical use information is compiled from...
Search relevance: 1.00 | Views last month: 12 | Catalog Last Checked: August 01, 2026 at 03:29 AM -
Background: Chemical toxicity testing is being transformed by advances in biology and computer modeling, concerns over animal use and the thousands of environmental chemicals lacking toxicity...
Search relevance: 1.00 | Views last month: 11 | Catalog Last Checked: August 01, 2026 at 03:29 AM -
We screened 44 chemicals in MCF7 cells in concentration response and generated HTTr data using the TempO-Seq hWTv1 assay. First, we provide an outline of the quality of the HTTr data based on a...
Search relevance: 1.00 | Views last month: 11 | Catalog Last Checked: August 03, 2026 at 12:47 AM -
Supplemental datafiles for journal article 'High-Throughput Transcriptomics Screen of ToxCast Chemicals in U-2 OS Cells'.
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The US Environmental Protection Agency’s (EPA) Distributed Structure-Searchable Toxicity (DSSTox) database, launched publicly in 2004, currently exceeds 875 K substances spanning hundreds of lists...
Search relevance: 1.00 | Views last month: 7 | Catalog Last Checked: August 03, 2026 at 12:46 AM -
Thousands of chemicals are directly added to or come in contact with food, many of which have undergone little to no toxicological evaluation. The landscape of the food-relevant chemical universe...
Search relevance: 1.00 | Views last month: 7 | Catalog Last Checked: August 03, 2026 at 12:41 AM -
The contents of the chemistry database, presently containing ~ 760,000 substances, are available as public domain data for download. The chemistry content underpinning the Dashboard has been...
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In the present study, we adapted an existing phenotypic profiling assay (“Cell Painting”, (Bray et al., 2016)) to be compatible with in-house microfluidics capabilities for 384-well culture...
Search relevance: 1.00 | Views last month: 5 | Catalog Last Checked: August 03, 2026 at 12:46 AM -
Aggregated Computational Toxicology Online Resource (AcTOR) is EPA's online aggregator of all the public sources of chemical toxicity data. ACToR aggregates data from over 1,000 public sources on...
Search relevance: 1.00 | Views last month: 5 | Catalog Last Checked: August 01, 2026 at 03:29 AM -
Dataset for Jurgelewicz, A. et al, 'Assessing the impact of in vitro xenobiotic metabolism on estrogenic chemical bioactivity in high-throughput profiling assays' published in Toxicology, Vol 517,...
Search relevance: 1.00 | Views last month: 4 | Catalog Last Checked: August 03, 2026 at 12:52 AM -
Chemical toxicity can arise from disruption of specific biomolecular functions or through more generalized cell stress and cytotoxicity-mediated processes. Here, concentration-dependent responses...
Search relevance: 1.00 | Views last month: 4 | Catalog Last Checked: August 03, 2026 at 12:41 AM -
The data set contains data for the following assays performed using 6PPD-quinone and/or 6PPD. 1) Larval fathead minnow transcriptomics; 2) larval fathead minnow EcoToxChips [6PPD-quinone only];...
Search relevance: 1.00 | Views last month: 4 | Catalog Last Checked: August 03, 2026 at 12:51 AM -
Dataset for Nyffeler et al., 'Application of Cell Painting for chemical hazard evaluation in support of screening-level chemical assessments', Toxicology & Applied Pharmacology, Vol 468, 116513,...
Search relevance: 1.00 | Views last month: 4 | Catalog Last Checked: August 03, 2026 at 12:49 AM -
Dataset for Harrill, J.A. et al., 'Signature Analysis of High-Throughput Transcriptomics Screening Data for Mechanistic Inference and Chemical Grouping' published in Toxicological Sciences,...
Search relevance: 1.00 | Views last month: 4 | Catalog Last Checked: August 03, 2026 at 12:50 AM -
The Distributed Structure Searchable Toxicity (DSSTox) online resource provides high quality chemical structures and annotations in association with toxicity data. It helps to build a data...
Search relevance: 1.00 | Views last month: 3 | Catalog Last Checked: August 01, 2026 at 03:29 AM -
Supplementary data for "Comparison of whole transcriptome and targeted RNA sequencing for ecological high-throughput transcriptomics". This dataset is associated with the following...
Search relevance: 1.00 | Views last month: 3 | Catalog Last Checked: August 03, 2026 at 12:52 AM -
Data from study assessing the utility of knowledgebase-leveraging of comprehensive environmental-contaminant-exposure datasets by comparing biological effects predicted on the basis of target...
Search relevance: 1.00 | Views last month: 3 | Catalog Last Checked: August 01, 2026 at 05:17 AM -
This dataset consists of data from in vitro developmental neurotoxicity new approach methodologies (DNT-NAMs). Assays include evaluations of proliferation, apoptosis, viability, neurite outgrowth,...
Search relevance: 1.00 | Views last month: 3 | Catalog Last Checked: August 03, 2026 at 12:48 AM -
Disruption of steroidogenesis by environmental chemicals can result in altered hormone levels causing adverse reproductive and developmental effects. A high-throughput assay using H295R human...
Search relevance: 1.00 | Views last month: 3 | Catalog Last Checked: August 03, 2026 at 12:41 AM -
Supplemental data for "LaLone CA, Blatz DJ, Jensen MA, Vliet SMF, Mayasich S, Mattingly KZ, Transue TR, Melendez W, Wilkinson A, Simmons CW, Ng C, Zhang C, Zhang Y. From Protein Sequence to...
Search relevance: 1.00 | Views last month: 3 | Catalog Last Checked: August 03, 2026 at 12:49 AM
