Found 15 datasets matching filters.
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Proteomics technologies enable profiling of autoantibody responses using biological fluids derived from patients with autoimmune disease. They provide a powerful tool to characterize autoreactive...
Search relevance: 1.00 | Views last month: 11 | Published on: 2025-09-07 -
Our goal in the present work was to determine whether male patients with untreated hypogonadism have an increased risk of developing rheumatic/autoimmune disease (RAD), and, if so, whether there...
Search relevance: 1.00 | Views last month: 2 | Published on: 2025-09-07 -
In the past 5 years, around 350 patients have received haematopoietic stem cell (HSC) transplantation for an autoimmune disease, with 275 of these registered in an international data base in Basel...
Search relevance: 1.00 | Views last month: 2 | Published on: 2025-09-07 -
We propose that the phenomenon of X-chromosome inactivation in females may constitute a risk factor for loss of T-cell tolerance; specifically that skewed X-chromosome inactivation in the thymus...
Search relevance: 1.00 | Views last month: 2 | Published on: 2025-09-07 -
Studies on immunological reconstitution after immune ablation and stem-cell therapy may yield important clues to our understanding of the pathogenesis of human autoimmune disease, due to the...
Search relevance: 1.00 | Views last month: 1 | Published on: 2025-09-07 -
Autoantibodies present in the serum of patients with a variety of inflammatory diseases have proven useful as diagnostic markers and as probes with which to elucidate biochemical and signaling...
Search relevance: 1.00 | Views last month: 1 | Published on: 2025-09-07 -
The substantial progress in our understanding of molecular and cellular biology has allowed us to design biological therapeutics ('biologicals') with defined targets and effector functions. These...
Search relevance: 1.00 | Views last month: 1 | Published on: 2025-09-07 -
Regulatory T cells prevent autoimmunity by suppressing the reactivity of potentially aggressive self-reactive T cells. Contact-dependent CD4+ CD25+ 'professional' suppressor cells and other...
Search relevance: 1.00 | Views last month: 1 | Published on: 2025-09-07 -
The anti-PM/Scl autoantibodies are known to characterize a subset of autoimmune patients with myositis, scleroderma (Scl), and the PM/Scl overlap syndrome. The major autoantigens that are...
Search relevance: 1.00 | Views last month: 0 | Published on: 2025-09-07 -
The role of autoantibodies in the etiology of autoimmune diseases remains unclear. However, an examination of the sequences of these autoantibodies can be informative. Antibody sequences that...
Search relevance: 1.00 | Views last month: 0 | Published on: 2025-09-07 -
Autoimmune diseases that are resistant to conventional treatment cause severe morbidity and even mortality. In the present study we demonstrate that complete remissions can be achieved in...
Search relevance: 1.00 | Views last month: 0 | Published on: 2025-09-07 -
Treatment of rats suffering from florid chronic progressive systemic arthritis or from chronic remitting/relapsing encephalomyelitis with autologous bone marrow transplantation (BMT) is highly...
Search relevance: 1.00 | Views last month: 0 | Published on: 2025-09-07 -
Inflammatory responses provoked by pathogens are antigen-specific in their induction but are nonspecific in their effects. Consequently, they are potentially damaging to the host that produces...
Search relevance: 1.00 | Views last month: 0 | Published on: 2025-09-07 -
Immune ablation and stem-cell therapy in autoimmune disease: Introduction
Search relevance: 1.00 | Views last month: 0 | Published on: 2025-09-07 -
Major advances in technology now drive how we approach questions in immunology, particularly in analyzing complex data sets commonly encountered in genomics and proteomics studies. Active areas of...
Search relevance: 1.00 | Views last month: 0 | Published on: 2025-09-07
