{"accessLevel": "public", "bureauCode": ["020:00"], "contactPoint": {"fn": "Angela Buckalew", "hasEmail": "mailto:buckalew.angela@epa.gov"}, "description": "Data pertaining to a NIS-expressing cell line, FRTL-5 and it's screening capabilities for confirming inhibitors of NIS-mediated iodide uptake. \n\nThis dataset is associated with the following publication:\nBuckalew, A., J. Wang, A. Murr, C. Deisenroth, W. Stewart, T. Stoker, and S. Laws. Evaluation of potential sodium-iodide symporter (NIS) inhibitors using a secondary Fischer rat thyroid follicular cell (FRTL-5) radioactive iodide uptake (RAIU) assay.   Archives of Toxicology. Springer, New York, NY, USA, 94(3): 873-885, (2020).", "distribution": [{"downloadURL": "https://pasteur.epa.gov/uploads/10.23719/1518689/FRTL-5%20dataset%20for%20science-hub.xlsx", "mediaType": "application/vnd.openxmlformats-officedocument.spreadsheetml.sheet", "title": "FRTL-5 dataset for science-hub.xlsx"}], "identifier": "https://doi.org/10.23719/1518689", "keyword": ["Sodium Iodide Symporter", "endocrine disruption", "high-throughput in vitro screening assay", "thyroid"], "license": "https://pasteur.epa.gov/license/sciencehub-license.html", "modified": "0019-06-09", "programCode": ["020:095"], "publisher": {"name": "U.S. EPA Office of Research and Development (ORD)", "subOrganizationOf": {"name": "U.S. Environmental Protection Agency", "subOrganizationOf": {"name": "U.S. Government"}}}, "references": ["https://doi.org/10.1007/s00204-020-02664-y"], "rights": null, "title": "Secondary screening method for sodium-iodide symporter inhibition utilizing FRTL-5 cells data set"}